prikaz prve stranice dokumenta Probe-Based Confocal Laser Endomicroscopy and Barrett’s Esophagus: Just a Scientific Toy or Significant Improvement in Diagnosis?
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Probe-Based Confocal Laser Endomicroscopy and Barrett’s Esophagus: Just a Scientific Toy or Significant Improvement in Diagnosis?
Digestive Diseases, 40 (2022), 1; 97-105. https://doi.org/10.1159/000516257
Vranić, Luka; Nadarević, Tin; Štimac, Davor

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Vranić, L., Nadarević, T. i Štimac, D. (2022). Probe-Based Confocal Laser Endomicroscopy and Barrett’s Esophagus: Just a Scientific Toy or Significant Improvement in Diagnosis?. Digestive Diseases, 40. (1), 97-105. doi: 10.1159/000516257

Vranić, Luka, et al. "Probe-Based Confocal Laser Endomicroscopy and Barrett’s Esophagus: Just a Scientific Toy or Significant Improvement in Diagnosis?." Digestive Diseases, vol. 40, br. 1, 2022, str. 97-105. https://doi.org/10.1159/000516257

Vranić, Luka, Tin Nadarević i Davor Štimac. "Probe-Based Confocal Laser Endomicroscopy and Barrett’s Esophagus: Just a Scientific Toy or Significant Improvement in Diagnosis?." Digestive Diseases 40, br. 1 (2022): 97-105. https://doi.org/10.1159/000516257

Vranić, L., Nadarević, T. i Štimac, D. (2022) 'Probe-Based Confocal Laser Endomicroscopy and Barrett’s Esophagus: Just a Scientific Toy or Significant Improvement in Diagnosis?', Digestive Diseases, 40(1), str. 97-105. doi: 10.1159/000516257

Vranić L, Nadarević T, Štimac D. Probe-Based Confocal Laser Endomicroscopy and Barrett’s Esophagus: Just a Scientific Toy or Significant Improvement in Diagnosis?. Digestive Diseases [Internet]. 01.04.2022. [pristupljeno 03.12.2024.];40(1):97-105. doi: 10.1159/000516257

L. Vranić, T. Nadarević i D. Štimac, "Probe-Based Confocal Laser Endomicroscopy and Barrett’s Esophagus: Just a Scientific Toy or Significant Improvement in Diagnosis?", Digestive Diseases, vol. 40, br. 1, str. 97-105, Travanj 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:533346. [Citirano: 03.12.2024.]

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Naslov (engleski)Probe-Based Confocal Laser Endomicroscopy and Barrett’s Esophagus: Just a Scientific Toy or Significant Improvement in Diagnosis?
AutorLuka Vranić
AutorTin Nadarević
AutorDavor Štimac
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za internu medicinu)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Background: Barrett’s esophagus (BE) requires surveillance to identify potential neoplasia at an early stage. The standard surveillance regimen includes random 4-quadrant biopsies by Seattle protocol. Main limitations of random biopsies are high risk of sampling error, difficulties in histology interpretation, common inadequate classification of pathohistological changes, increased risk of bleeding, and time necessary to acquire the final diagnosis. Probe-based confocal laser endomicroscopy (pCLE) has emerged as a potential tool with an aim to overcome these obvious limitations. Summary: pCLE represents a real-time microscopic imaging method that offers evaluation of epithelial and subepithelial structures with 1,000-fold magnification. In theory, pCLE has potential to eliminate the need for biopsy in BE patients. The main advantages would be real-time diagnosis and decision-making, greater diagnostic accuracy, and evaluation of larger area compared to random biopsies. Clinical pCLE studies in the esophagus show high diagnostic accuracy, and its high negative predictive value offers high reliability and confidence to exclude dysplastic and neoplastic lesions. However, it still cannot replace histopathology due to lower positive predictive value and sensitivity. Key Messages: Despite promising results, its role in routine use in patients with BE remains questionable primarily due to lack of well-organized double-blind randomized trials.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaDigestive Diseases
Brojčani podacivol. 40, br. 1, str. 97-105
p-ISSN0257-2753
e-ISSN1421-9875
DOIhttps://doi.org/10.1159/000516257
URN:NBNurn:nbn:hr:184:533346
Datum objave publikacije2022-04-01
URL dokumentahttps://www.karger.com/Article/FullText/516257
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2022-01-26 11:12:25