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Viral Interactions with Adaptor-Protein Complexes: A Ubiquitous Trait among Viral Species
International Journal of Molecular Sciences, 22 (2021), 10; 5274. https://doi.org/10.3390/ijms22105274
Strazic Geljic, Ivana; Kucan Brlic, Paola; Musak, Lucija; Karner, Dubravka; Ambriović-Ristov, Andreja; Jonjic, Stipan; Schu, Peter; Rovis, Tihana Lenac

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Strazic Geljic, I., Kucan Brlic, P., Musak, L., Karner, D., Ambriović Ristov, A., Jonjic, S. ... Rovis, T. L. (2021). Viral Interactions with Adaptor-Protein Complexes: A Ubiquitous Trait among Viral Species. International Journal of Molecular Sciences, 22. (10). doi: 10.3390/ijms22105274

Strazic Geljic, Ivana, et al. "Viral Interactions with Adaptor-Protein Complexes: A Ubiquitous Trait among Viral Species." International Journal of Molecular Sciences, vol. 22, br. 10, 2021. https://doi.org/10.3390/ijms22105274

Strazic Geljic, Ivana, Paola Kucan Brlic, Lucija Musak, Dubravka Karner, Andreja Ambriović Ristov, Stipan Jonjic, Peter Schu i Tihana Lenac Rovis. "Viral Interactions with Adaptor-Protein Complexes: A Ubiquitous Trait among Viral Species." International Journal of Molecular Sciences 22, br. 10 (2021). https://doi.org/10.3390/ijms22105274

Strazic Geljic, I., et al. (2021) 'Viral Interactions with Adaptor-Protein Complexes: A Ubiquitous Trait among Viral Species', International Journal of Molecular Sciences, 22(10). doi: 10.3390/ijms22105274

Strazic Geljic I, Kucan Brlic P, Musak L, Karner D, Ambriović Ristov A, Jonjic S, i sur.. Viral Interactions with Adaptor-Protein Complexes: A Ubiquitous Trait among Viral Species. International Journal of Molecular Sciences [Internet]. 17.05.2021. [pristupljeno 15.11.2024.];22(10). doi: 10.3390/ijms22105274

I. Strazic Geljic, et al., "Viral Interactions with Adaptor-Protein Complexes: A Ubiquitous Trait among Viral Species", International Journal of Molecular Sciences, vol. 22, br. 10, Svibanj 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:195997. [Citirano: 15.11.2024.]

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Naslov (engleski)Viral Interactions with Adaptor-Protein Complexes: A Ubiquitous Trait among Viral Species
AutorIvana Strazic Geljic
AutorPaola Kucan Brlic
AutorLucija Musak
AutorDubravka Karner
AutorAndreja Ambriović-Ristov
AutorStipan Jonjic
AutorPeter Schu
AutorTihana Lenac Rovis
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Centar za proteomiku)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za histologiju i embriologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Sažetak (engleski)
Numerous viruses hijack cellular protein trafficking pathways to mediate cell entry or to rearrange membrane structures thereby promoting viral replication and antagonizing the immune response. Adaptor protein complexes (AP), which mediate protein sorting in endocytic and secretory transport pathways, are one of the conserved viral targets with many viruses possessing AP-interacting motifs. We present here different mechanisms of viral interference with AP complexes and the functional consequences that allow for efficient viral propagation and evasion of host immune defense. The ubiquity of this phenomenon is evidenced by the fact that there are representatives for AP interference in all major viral families, covered in this review. The best described examples are interactions of human immunodeficiency virus and human herpesviruses with AP complexes. Several other viruses, like Ebola, Nipah, and SARS-CoV-2, are pointed out as high priority disease-causative agents supporting the need for deeper understanding of virus-AP interplay which can be exploited in the design of novel antiviral therapies.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaInternational Journal of Molecular Sciences
Brojčani podacivol. 22, br. 10, 5274
e-ISSN1422-0067
DOIhttps://doi.org/10.3390/ijms22105274
URN:NBNurn:nbn:hr:184:195997
Datum objave publikacije2021-05-17
ProjektŠifra: IP-2020-02-6617
Naziv (hrvatski): Imunoregulatorna uloga proteina PrPC u imunološkom antivirusnom odgovoru i otpornosti na citomegalovirusnu infekciju
Kratica: PrImReg
Voditelj: Tihana Lenac Roviš
Pravna nadležnost: Hrvatska
Financijer: HRZZ
Linija financiranja: IP
ProjektŠifra: IP-2019-04-1577
Naziv (hrvatski): Integrin alpha V beta 5-povezane fokalne i retikularne adhezije u melanomu
Naziv (engleski): Integrin alpha V beta 5-associated Focal and Reticular Adhesions in Melanoma
Kratica: AdMeFoRe
Voditelj: Andreja Ambriović Ristov
Pravna nadležnost: Hrvatska
Financijer: HRZZ
Linija financiranja: IP
ProjektŠifra: uniri-biomed-18-233
Naziv (hrvatski): Međuodnos proteina PrPc i imunološkog sustava tijekom virusne infekcije
Naziv (engleski): The role of PrPC in the immune system upon exposure to viruses
Voditelj: Tihana Lenac Roviš
Pravna nadležnost: Hrvatska
Financijer: NadSve
Linija financiranja: Sveučilište u Rijeci
ProjektŠifra: N/A
Naziv (hrvatski): Centar izvrsnosti za virusnu imunologiju i cjepiva
Naziv (engleski): Centre of Excellence for Research in Viral Immunology and the Development of New Vaccines
Kratica: CERVirVac
Voditelj: Stipan Jonjić
Pravna nadležnost: Hrvatska
Financijer: MZOS
Linija financiranja: ZCI
URL dokumentahttps://www.mdpi.com/1422-0067/22/10/5274
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2021-09-17 12:37:26