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Study of vitamin D receptor gene polymorphisms in a cohort of myocardial infarction patients with coronary artery disease
BMC Cardiovascular Disorders, 21 (2021), 1; 188. https://doi.org/10.1186/s12872-021-01959-x
Raljević, Damir; Peršić, Viktor; Markova-Car, Elitza; Cindrić, Leon; Miškulin, Rajko; Žuvić, Marta; Kraljević Pavelić, Sandra

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Raljević, D., Peršić, V., Markova Car, E., Cindrić, L., Miškulin, R., Žuvić, M. i Kraljević Pavelić, S. (2021). Study of vitamin D receptor gene polymorphisms in a cohort of myocardial infarction patients with coronary artery disease. BMC Cardiovascular Disorders, 21. (1). doi: 10.1186/s12872-021-01959-x

Raljević, Damir, et al. "Study of vitamin D receptor gene polymorphisms in a cohort of myocardial infarction patients with coronary artery disease." BMC Cardiovascular Disorders, vol. 21, br. 1, 2021. https://doi.org/10.1186/s12872-021-01959-x

Raljević, Damir, Viktor Peršić, Elitza Markova Car, Leon Cindrić, Rajko Miškulin, Marta Žuvić i Sandra Kraljević Pavelić. "Study of vitamin D receptor gene polymorphisms in a cohort of myocardial infarction patients with coronary artery disease." BMC Cardiovascular Disorders 21, br. 1 (2021). https://doi.org/10.1186/s12872-021-01959-x

Raljević, D., et al. (2021) 'Study of vitamin D receptor gene polymorphisms in a cohort of myocardial infarction patients with coronary artery disease', BMC Cardiovascular Disorders, 21(1). doi: 10.1186/s12872-021-01959-x

Raljević D, Peršić V, Markova Car E, Cindrić L, Miškulin R, Žuvić M, i sur.. Study of vitamin D receptor gene polymorphisms in a cohort of myocardial infarction patients with coronary artery disease. BMC Cardiovascular Disorders [Internet]. 16.04.2021. [pristupljeno 15.11.2024.];21(1). doi: 10.1186/s12872-021-01959-x

D. Raljević, et al., "Study of vitamin D receptor gene polymorphisms in a cohort of myocardial infarction patients with coronary artery disease", BMC Cardiovascular Disorders, vol. 21, br. 1, Travanj 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:293984. [Citirano: 15.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:293984
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Podaci o radu
Naslov (engleski)Study of vitamin D receptor gene polymorphisms in a cohort of myocardial infarction patients with coronary artery disease
AutorDamir Raljević
AutorViktor Peršić
AutorElitza Markova-Car
MBZ: 284336
AutorLeon Cindrić
AutorRajko Miškulin
AutorMarta Žuvić
AutorSandra Kraljević Pavelić
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za rehabilitacijsku i sportsku medicinu)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Genetika, genomika i proteomika čovjeka
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Background: Vitamin D deficiency is associated with cardiovascular diseases, including coronary artery diseases (CAD). As vitamin D manifests its biological function through its vitamin D receptor (VDR), VDR gene polymorphisms potentially affect VDR functionality and vitamin D activity. Therefore, the objective of this study was to analyze three well-studied VDR gene polymorphisms- Fok1 (rs2228570), BsmI (rs1544410) and Taq1 (rs731236)-in a cohort of CAD patients after acute myocardial infarction. Methods: In the presented cross-sectional study, 155 participants with CAD after acute myocardial infarction and 104 participants in a control group without CAD were enrolled. The participants in both groups were Caucasians of European origin. The genotyping of VDR polymorphisms rs2228570, rs1544410 and rs731236 was assessed by RT-PCR. Results: The results show an association between the T/T genotype of the BsmI (rs1544410) and the G/G genotype of the Taq1 (rs731236) VDR polymorphism and CAD patients after acute myocardial infarction. There was no association between the Fok1 (rs2228570) VDR polymorphism and CAD patients after acute myocardial infarction. Conclusion: The presented results suggest a potential association of the BsmI (rs1544410) and Taq1 (rs731236) VDR polymorphisms with CAD patients after myocardial infarction.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaBMC Cardiovascular Disorders
Brojčani podacivol. 21, br. 1, 188
e-ISSN1471-2261
DOIhttps://doi.org/10.1186/s12872-021-01959-x
URN:NBNurn:nbn:hr:184:293984
Datum objave publikacije2021-04-16
ProjektŠifra: uniri-biomed-18-257
Naziv (hrvatski): Cirlkadijalni geni u planocelularnog karcinoma larinksa
Naziv (engleski): Circadian genes in laryngeal squamous cell carcinoma
Voditelj: Elitza Petkova Markova-Car
Pravna nadležnost: Hrvatska
Financijer: NadSve
Linija financiranja: Sveučilište u Rijeci
URL dokumentahttps://bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-021-01959-x
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2021-04-20 20:04:03