prikaz prve stranice dokumenta Vitamin D receptor polymorphisms in spontaneous preterm birth: a case-control study
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Vitamin D receptor polymorphisms in spontaneous preterm birth: a case-control study
Croatian medical journal, 61 (2020), 4; 338-345. urn:nbn:hr:184:843212
Gašparović Krpina, Milena; Barišić, Anita; Peterlin, Ana; Tul, Nataša; Ostojić, Saša; Peterlin, Borut; Pereza, Nina

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Gašparović Krpina, M., Barišić, A., Peterlin, A., Tul, N., Ostojić, S., Peterlin, B. i Pereza, N. (2020). Vitamin D receptor polymorphisms in spontaneous preterm birth: a case-control study. Croatian medical journal, 61. (4), 338-345. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:184:843212

Gašparović Krpina, Milena, et al. "Vitamin D receptor polymorphisms in spontaneous preterm birth: a case-control study." Croatian medical journal, vol. 61, br. 4, 2020, str. 338-345. https://urn.nsk.hr/urn:nbn:hr:184:843212

Gašparović Krpina, Milena, Anita Barišić, Ana Peterlin, Nataša Tul, Saša Ostojić, Borut Peterlin i Nina Pereza. "Vitamin D receptor polymorphisms in spontaneous preterm birth: a case-control study." Croatian medical journal 61, br. 4 (2020): 338-345. https://urn.nsk.hr/urn:nbn:hr:184:843212

Gašparović Krpina, M., et al. (2020) 'Vitamin D receptor polymorphisms in spontaneous preterm birth: a case-control study', Croatian medical journal, 61(4), str. 338-345. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:184:843212 (Datum pristupa: 14.11.2024.)

Gašparović Krpina M, Barišić A, Peterlin A, Tul N, Ostojić S, Peterlin B, i sur.. Vitamin D receptor polymorphisms in spontaneous preterm birth: a case-control study. Croatian medical journal [Internet]. 2020. [pristupljeno 14.11.2024.];61(4):338-345. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:843212

M. Gašparović Krpina, et al., "Vitamin D receptor polymorphisms in spontaneous preterm birth: a case-control study", Croatian medical journal, vol. 61, br. 4, str. 338-345, 2020. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:843212. [Citirano: 14.11.2024.]

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Naslov (engleski)Vitamin D receptor polymorphisms in spontaneous preterm birth: a case-control study
AutorMilena Gašparović Krpina
AutorAnita Barišić
AutorAna Peterlin
AutorNataša Tul
AutorSaša Ostojić
MBZ: 376772
AutorBorut Peterlin
AutorNina Pereza
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za medicinsku biologiju i genetiku)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Sažetak (engleski)
Aim To evaluate the association between the FokI (rs2228570), ApaI (rs7975232), Bsml (rs1544410), TaqI (rs731236), and Cdx2 (rs11568820) single nucleotide polymorphisms (SNPs) in the vitamin D receptor (VDR) gene and spontaneous preterm birth (SPTB), as well as their effect on clinical characteristics of women with SPTB and their newborns. Methods This case-control study enrolled women who gave birth at the Department of Obstetrics and Gynecology, University Medical Center Ljubljana between 2010 to 2019. Cases were 118 women with spontaneous initiation of PTB after natural conception and 119 controls with a term singleton delivery after an uncomplicated pregnancy. The molecular analysis of VDR SNPs employed polymerase chain reaction and restriction fragment length polymorphism. Results Patients and controls did not significantly differ in the distribution of genotype or allele SNP frequencies. However, the FokI polymorphism had a significant effect on newborn birth weight in women with SPTB but not in controls (F=5.17, P=0.007, one-way ANOVA with post-hoc Scheffe test), with newborns of FokI TT carriers having the lowest birth weight (P=0.011). No other VDR SNP was associated with any other clinical characteristic of women with SPTB and their newborns. Conclusion The TT genotype of the VDR FokI polymorphism is associated with newborn birth weight in women of European origin with SPTB.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCroatian medical journal
Brojčani podacivol. 61, br. 4, str. 338-345
p-ISSN0353-9504
URN:NBNurn:nbn:hr:184:843212
Datum objave publikacije2020
URL dokumentahttp://bib.irb.hr/1077811
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2020-09-17 13:51:59