Aim: Prothetic rehabilitation after lower limb amputation includes all complex procedures and interactions between the rehabilitation team and the patient aimed for establishing a safe and stable walk with the prosthesis. After being released from the rehabilitation center, the patient uses the prosthesis, according to age, lifestyle and the environment in which he lives. Aim: The aim of the paper is to evaluate the success of the prosthetic rehabilitation after lower limb amputation patients using Amputee Mobility Predictor (AMP) and walking speed measures. Patients and methods: The following patients’ data ware taken from the database at the Department of Physical and Rehabilitation Medicine of the Clinical Hospital Center Rijeka, used in purpose of this work only, and stayed anonymous according to the Helsinki Declaration: age, sex, type and side of amputation, AMP, walking speed and the time spent in the prosthesis. From the 100 patients with amputation, 62 of them was transtibial (TT) and 38 transfemoral (TF). The AMP index was established for all patients prior to the rehabilitation procedure (AMPnoPRO) and after the completed rehabilitation procedure (AMPPRO). Results: After the prosthetic rehabilitation, a statistically significant difference in ultimate mobility (AMP: p < 0,001) and walking speed (p = 0.002) between the TT and the TF group was established, respectively, in a patients with a lower level of amputation (TT). A statistically significant correlation between the time spent in the prosthesis and walking speed and AMP index (p < 0.001) was also established. Conclusion: The level of amputation is an important factor contributing to the ultimate outcome of the rehabilitation process, and a higher level of amputation in patients (TF) is one form of limitation for better success compared to patients with lower amputation levels (TT).