prikaz prve stranice dokumenta Diabetes, Dipeptidyl Peptidase iv and Wound Healing: from Basic Science to Therapeutic Possibilities
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Diabetes, Dipeptidyl Peptidase iv and Wound Healing: from Basic Science to Therapeutic Possibilities
Open Access Journal of Biomedical Engineering and Biosciences, 2 (2018), 5; 230-236. https://doi.org/10.32474/OAJBEB.2018.02.000147
Batičić Pučar, Lara; Sharbini, Alaa; Varljen, Jadranka; Pernjak Pugel, Ester; Grčić, Antonijo; Detel, Dijana

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Batičić Pučar, L., Sharbini, A., Varljen, J., Pernjak Pugel, E., Grčić, A. i Detel, D. (2018). Diabetes, Dipeptidyl Peptidase iv and Wound Healing: from Basic Science to Therapeutic Possibilities. Open Access Journal of Biomedical Engineering and Biosciences, 2. (5), 230-236. doi: 10.32474/OAJBEB.2018.02.000147

Batičić Pučar, Lara, et al. "Diabetes, Dipeptidyl Peptidase iv and Wound Healing: from Basic Science to Therapeutic Possibilities." Open Access Journal of Biomedical Engineering and Biosciences, vol. 2, br. 5, 2018, str. 230-236. https://doi.org/10.32474/OAJBEB.2018.02.000147

Batičić Pučar, Lara, Alaa Sharbini, Jadranka Varljen, Ester Pernjak Pugel, Antonijo Grčić i Dijana Detel. "Diabetes, Dipeptidyl Peptidase iv and Wound Healing: from Basic Science to Therapeutic Possibilities." Open Access Journal of Biomedical Engineering and Biosciences 2, br. 5 (2018): 230-236. https://doi.org/10.32474/OAJBEB.2018.02.000147

Batičić Pučar, L., et al. (2018) 'Diabetes, Dipeptidyl Peptidase iv and Wound Healing: from Basic Science to Therapeutic Possibilities', Open Access Journal of Biomedical Engineering and Biosciences, 2(5), str. 230-236. doi: 10.32474/OAJBEB.2018.02.000147

Batičić Pučar L, Sharbini A, Varljen J, Pernjak Pugel E, Grčić A, Detel D. Diabetes, Dipeptidyl Peptidase iv and Wound Healing: from Basic Science to Therapeutic Possibilities. Open Access Journal of Biomedical Engineering and Biosciences [Internet]. 10.09.2018. [pristupljeno 11.11.2024.];2(5):230-236. doi: 10.32474/OAJBEB.2018.02.000147

L. Batičić Pučar, A. Sharbini, J. Varljen, E. Pernjak Pugel, A. Grčić i D. Detel, "Diabetes, Dipeptidyl Peptidase iv and Wound Healing: from Basic Science to Therapeutic Possibilities", Open Access Journal of Biomedical Engineering and Biosciences, vol. 2, br. 5, str. 230-236, Rujan 2018. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:786960. [Citirano: 11.11.2024.]

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Podaci o radu
Naslov (engleski)Diabetes, Dipeptidyl Peptidase iv and Wound Healing: from Basic Science to Therapeutic Possibilities
AutorLara Batičić Pučar
AutorAlaa Sharbini
AutorJadranka Varljen
AutorEster Pernjak Pugel
AutorAntonijo Grčić
AutorDijana Detel
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za histologiju i embriologiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za medicinsku kemiju, biokemiju i kliničku kemiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Hyperglycemia, often accompanied with various complications such as chronic ulcers, represents a major socio-economic health problem. Dipeptidyl peptidase IV or CD26 molecule (DPP IV/CD26), is an omnipresent transmembrane protein with significant involvements in different physiological and pathological processes. It has been recognized as a therapeutic option in the treatment of hyperglycemia, especially in patients suffering from type 2 diabetes, given its capability to regulate the biological activity of incretins, which are major regulators of glucose homeostasis. Furthermore, DPP IV/CD26 has been indicated to be involved in the regulation of inflammatory processes as well as cell proliferation and angiogenesis. New scientific evidence shows that inhibition of DPP IV/CD26 leads to a more efficacious healing of chronic ulcers in diabetic patients as well as in mice models of wounded tissue restoration. However, the role of DPP IV/CD26 in the process of wound healing in hyperglycemia is not entirely known. Our aim was to summarize most important findings on the involvement of DPP IV/CD26 in the regulation of glycemia as well as tissue regeneration and reparation. This work reviews basic biochemical.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaOpen Access Journal of Biomedical Engineering and Biosciences
Brojčani podacivol. 2, br. 5, str. 230-236
e-ISSN2637-4579
DOIhttps://doi.org/10.32474/OAJBEB.2018.02.000147
URN:NBNurn:nbn:hr:184:786960
Datum objave publikacije2018-09-10
URL dokumentahttps://www.lupinepublishers.com/biomedical-sciences-journal/fulltext/diabetes-dipeptidyl-peptidase-iv-and-wound-healing-from-basic-science-to-therapeutic-possibilities.ID.000147.php
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2018-12-03 15:13:36