prikaz prve stranice dokumenta Interlaboratory concordance in HER-2 positive breast cancer
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Interlaboratory concordance in HER-2 positive breast cancer
Acta clinica Croatica, 54 (2015), 4; 479-485. urn:nbn:hr:184:926373
Jonjić, Nives; Mustać, Elvira; Tomić, Snježana; Razumović Jakić, Jasminka; Šarčević, Božena; Blažičević, Valerija; Labinac Peteh, Loredana; Švagelj, Dražen; Kopjar, Andrina; Šikić Lisica, Nataša; Vrbičić, Branka; Borić, Igor

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Jonjić, N., Mustać, E., Tomić, S., Razumović Jakić, J., Šarčević, B., Blažičević, V. ... Borić, I. (2015). Interlaboratory concordance in HER-2 positive breast cancer. Acta clinica Croatica, 54. (4), 479-485. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:184:926373

Jonjić, Nives, et al. "Interlaboratory concordance in HER-2 positive breast cancer." Acta clinica Croatica, vol. 54, br. 4, 2015, str. 479-485. https://urn.nsk.hr/urn:nbn:hr:184:926373

Jonjić, Nives, Elvira Mustać, Snježana Tomić, Jasminka Razumović Jakić, Božena Šarčević, Valerija Blažičević, Loredana Labinac Peteh, et al. "Interlaboratory concordance in HER-2 positive breast cancer." Acta clinica Croatica 54, br. 4 (2015): 479-485. https://urn.nsk.hr/urn:nbn:hr:184:926373

Jonjić, N., et al. (2015) 'Interlaboratory concordance in HER-2 positive breast cancer', Acta clinica Croatica, 54(4), str. 479-485. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:184:926373 (Datum pristupa: 13.11.2024.)

Jonjić N, Mustać E, Tomić S, Razumović Jakić J, Šarčević B, Blažičević V, i sur.. Interlaboratory concordance in HER-2 positive breast cancer. Acta clinica Croatica [Internet]. 2015. [pristupljeno 13.11.2024.];54(4):479-485. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:926373

N. Jonjić, et al., "Interlaboratory concordance in HER-2 positive breast cancer", Acta clinica Croatica, vol. 54, br. 4, str. 479-485, 2015. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:926373. [Citirano: 13.11.2024.]

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Podaci o radu
Naslov (engleski)Interlaboratory concordance in HER-2 positive breast cancer
AutorNives Jonjić
AutorElvira Mustać
AutorSnježana Tomić
AutorJasminka Razumović Jakić
AutorBožena Šarčević
MBZ: 87995
AutorValerija Blažičević
MBZ: 232314
AutorLoredana Labinac Peteh
MBZ: 304022
AutorDražen Švagelj
MBZ: 224894
AutorAndrina Kopjar
AutorNataša Šikić Lisica
AutorBranka Vrbičić
AutorIgor Borić
MBZ: 253942
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za opću patologiju i patološku anatomiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Patologija
Sažetak (engleski)
Accurate assessment of HER-2 status is essential for identifying patients who will benefit from HER-2 targeted therapy. The aim of the present study was to show results on the concordance between local and central laboratory testing results in HER-2 positive breast cancer patients. In cases with discordant findings, the immunohistochemical (IHC) and/or in situ hybridization (FISH/SISH) analysis was performed in central laboratories. A total of 104 out of 143 (72.72%) breast carcinomas cases were HER-2 positive (score 3+), while nearly 14% of tumors (20/43) showed weak (score 2+) and 12% (19/143) negative IHC staining (score 0 and 1+). After repeated IHC and ISH, 88% (126/143) were classified as HER-2 positive and 12% (17/143) as HER-2 negative cases. The results obtained are in agreement with many studies that confirmed similar discordance in HER-2 testing by IHC and/or FISH between local and central laboratory. Thus, our findings as well as of other studies support the importance of regular quality assessment of the staining procedures performed and consistency of interpretation of HER-2 test results.
Ključne riječi (engleski)
Jezikhrvatski
Vrsta publikacijeStručni rad - Stručni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaActa clinica Croatica
Brojčani podacivol. 54, br. 4, str. 479-485
p-ISSN1333-9451
URN:NBNurn:nbn:hr:184:926373
Datum objave publikacije2015
URL dokumentahttp://bib.irb.hr/814237
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2018-11-13 16:13:09