Multiple Sclerosis (MS) is a chronic neurological disease with an unpredictable course, affecting the insulation surrounding nerve fibres (axons) of the central nervous system (CNS) and the axons themselves. The exact cause of MS is not known. The most common symptoms of MS include loss of vision and/or double vision, stiffness, weak-ness, imbalance, loss of co-ordination and dexterity, numbness, pain, problems with bladder and bowel control, fatigue, speech and swallowing disorders, sexual difficulties, emotional changes and intellectual impairment. The type and number of symptoms vary greatly from one individual to another, depending on where the damage occurs in the brain or spinal cord. MS is the most common cause of neurological disability affecting people in their productive years, between 15 and 55 years of age. The total number of people with MS in Europe is estimated to be more than 600.000. MS affects women twice as much than men. MS is not a classic hereditary disease. Multiple Sclerosis has physical and psychosocial consequences, which usually have enormous longterm impacts on almost every aspect of the lives of persons with MS and their families. Rehabilitation should therefore improve the ability to perform basic daily functional activities, mobility, occupation, communication and social integration. It is required in many different kinds of impairments and disabilities, especially decreased mobility and dexterity, bladder and bowel dysfunction, communication and swallowing disorders, and cognitive impairment.