Spinal cord injury (SCI) is a difficult medical condition for which there is no adequate medication. It results in a large majority of physical disabilities and damaged function of many organic systems. By the outset, we differentiate the traumatic and atraumatic form of SCI. The traumatic form of SCI is more common in younger populations up to 30 years, mostly male population. The reason is more risky behavior and more frequent participation in traffic accidents and sport injuries. The most common causes of traumatic SCI are car traffic accidents, then motorcycle and bicycle crashes, falls and violent spinal injuries. Atraumatic SCI is the result of tumors, bacterial or viral infections, and neurodegenerative diseases, vascular or metabolic damage. It is more common for women than men, and also for the younger population between 20 and 40 years. Damage causes neurological failure, complete or partial loss of sensation and motor function and disturbed function of sphincter and autonomous functions. Diagnosis and examination of the spinal cord injury can be immediately performed by neurological examination. The examination can be done with immediate effect after injury, even in people with an unstable spine. All dermatomes and myotomes of the extremities are examined to determine the last intact spinal cord with a preserved motor and sensory function. Diagnosis also uses image methods such as RTG, CT, and MR to determine and locate the injury with certainty. Treatment of spinal cord injury begins immediately after hospitalization. It is a difficult and complex process that lasts many years. The outcome of the treatment depends on a number of components. Perhaps the most important are expertise of the interdisciplinary team around the patient and the patient's own will and desire for progress and recovery. The treatment consists of three phases: acute care of SCI, rehabilitation and chronic stage of injury. An additional phase of treatment may include prevention and treatment of secondary complications carried by SCI .