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Breast Infiltrating Ductal Carcinoma: Analysis of Hormone, HER-2 Receptors and Ki-67 Proliferation Marker
Collegium antropologicum, 32 (2008), 3; 741-746. urn:nbn:hr:184:436234
Mustać, Elvira; Zamolo, Gordana; Petković, Marija; Đorđević, Gordana; Radić, Jelena; Grgurević, Emina; Batinac, Tanja

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Mustać, E., Zamolo, G., Petković, M., Đorđević, G., Radić, J., Grgurević, E. i Batinac, T. (2008). Breast Infiltrating Ductal Carcinoma: Analysis of Hormone, HER-2 Receptors and Ki-67 Proliferation Marker. Collegium antropologicum, 32. (3), 741-746. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:184:436234

Mustać, Elvira, et al. "Breast Infiltrating Ductal Carcinoma: Analysis of Hormone, HER-2 Receptors and Ki-67 Proliferation Marker." Collegium antropologicum, vol. 32, br. 3, 2008, str. 741-746. https://urn.nsk.hr/urn:nbn:hr:184:436234

Mustać, Elvira, Gordana Zamolo, Marija Petković, Gordana Đorđević, Jelena Radić, Emina Grgurević i Tanja Batinac. "Breast Infiltrating Ductal Carcinoma: Analysis of Hormone, HER-2 Receptors and Ki-67 Proliferation Marker." Collegium antropologicum 32, br. 3 (2008): 741-746. https://urn.nsk.hr/urn:nbn:hr:184:436234

Mustać, E., et al. (2008) 'Breast Infiltrating Ductal Carcinoma: Analysis of Hormone, HER-2 Receptors and Ki-67 Proliferation Marker', Collegium antropologicum, 32(3), str. 741-746. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:184:436234 (Datum pristupa: 12.11.2024.)

Mustać E, Zamolo G, Petković M, Đorđević G, Radić J, Grgurević E, i sur.. Breast Infiltrating Ductal Carcinoma: Analysis of Hormone, HER-2 Receptors and Ki-67 Proliferation Marker. Collegium antropologicum [Internet]. 02.09.2008. [pristupljeno 12.11.2024.];32(3):741-746. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:436234

E. Mustać, et al., "Breast Infiltrating Ductal Carcinoma: Analysis of Hormone, HER-2 Receptors and Ki-67 Proliferation Marker", Collegium antropologicum, vol. 32, br. 3, str. 741-746, Rujan 2008. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:436234. [Citirano: 12.11.2024.]

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Podaci o radu
Naslov (engleski)Breast Infiltrating Ductal Carcinoma: Analysis of Hormone, HER-2 Receptors and Ki-67 Proliferation Marker
AutorElvira Mustać
AutorGordana Zamolo
AutorMarija Petković
AutorGordana Đorđević
AutorJelena Radić
AutorEmina Grgurević
AutorTanja Batinac
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za dermatovenerologiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za onkologiju i radioterapiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za opću patologiju i patološku anatomiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Patologija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Onkologija
Sažetak (engleski)
The aim of this study was to analyse breast carcinomas with discordant receptor status, probably hormonal dependent (estrogen receptor (ER) positive, progesterone receptor (PR) negative or ER-PR+ subgroup profile) infiltrating ductal breast carcinomas not otherwise specified (IDC NOS). Specimens from 90 IDC NOS were grouped into three categories according to hormonal status: dependent (D) (ER+PR+), probably dependent (PD) (ER+PR- or ER-PR+) and non-dependent (ND) (ER-PR-); they were evaluated considering some established prognostic parameters in breast carcinomas. Statistically significant difference was found between tumor receptor status distribution and menopausal status (p= 0.0235), age of the patients (p=0.000467), histological grade (p=0.000003), vascular invasion (p=0.006), HER-2 status (p=0.0039) and Ki-67 proliferation rate (p=0.000311). D tumors were found exclusively in post-menopausal patients (average age 68.9 years), most of which had intermediate (II) grade, without vascular invasion, with HER-2 status score predominantly 0 or 1+ and lower Ki-67 proliferation rate. PD tumors were found predominantly in younger post-menopausal patients (average age 57.5 years), with vascular invasion found in 23% of the cases. ND tumors mostly had higher histological grade, showed the highest percentage of the Ki-67 positive tumor cells and vascular invasion in 30% of the cases. We conclude that the patients with PD breast carcinomas were younger post-menopausal women with the tumors moderately differentiated, HER-2 score 0 or 1+ and with lower Ki-67 proliferation rate.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCollegium antropologicum
Brojčani podacivol. 32, br. 3, str. 741-746
p-ISSN0350-6134
URN:NBNurn:nbn:hr:184:436234
Datum objave publikacije2008-09-02
URL dokumentahttp://hrcak.srce.hr/27056
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2017-09-17 19:11:05