prikaz prve stranice dokumenta Cell Apoptosis as Assessed by M30 Expression in Keratoacanthoma and Squamous Cell Carcinoma
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Cell Apoptosis as Assessed by M30 Expression in Keratoacanthoma and Squamous Cell Carcinoma
Collegium antropologicum, 32 (2008), 2; 499-504. urn:nbn:hr:184:809787
Batinac, Tanja; Zamolo, Gordana; Brumini, Gordana; Biljan, Darko; Petranović, Duška; Trošelj-Vukić, Biserka

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Batinac, T., Zamolo, G., Brumini, G., Biljan, D., Petranović, D. i Trošelj Vukić, B. (2008). Cell Apoptosis as Assessed by M30 Expression in Keratoacanthoma and Squamous Cell Carcinoma. Collegium antropologicum, 32. (2), 499-504. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:184:809787

Batinac, Tanja, et al. "Cell Apoptosis as Assessed by M30 Expression in Keratoacanthoma and Squamous Cell Carcinoma." Collegium antropologicum, vol. 32, br. 2, 2008, str. 499-504. https://urn.nsk.hr/urn:nbn:hr:184:809787

Batinac, Tanja, Gordana Zamolo, Gordana Brumini, Darko Biljan, Duška Petranović i Biserka Trošelj Vukić. "Cell Apoptosis as Assessed by M30 Expression in Keratoacanthoma and Squamous Cell Carcinoma." Collegium antropologicum 32, br. 2 (2008): 499-504. https://urn.nsk.hr/urn:nbn:hr:184:809787

Batinac, T., et al. (2008) 'Cell Apoptosis as Assessed by M30 Expression in Keratoacanthoma and Squamous Cell Carcinoma', Collegium antropologicum, 32(2), str. 499-504. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:184:809787 (Datum pristupa: 13.11.2024.)

Batinac T, Zamolo G, Brumini G, Biljan D, Petranović D, Trošelj Vukić B. Cell Apoptosis as Assessed by M30 Expression in Keratoacanthoma and Squamous Cell Carcinoma. Collegium antropologicum [Internet]. 07.07.2008. [pristupljeno 13.11.2024.];32(2):499-504. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:809787

T. Batinac, G. Zamolo, G. Brumini, D. Biljan, D. Petranović i B. Trošelj Vukić, "Cell Apoptosis as Assessed by M30 Expression in Keratoacanthoma and Squamous Cell Carcinoma", Collegium antropologicum, vol. 32, br. 2, str. 499-504, Srpanj 2008. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:809787. [Citirano: 13.11.2024.]

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Naslov (engleski)Cell Apoptosis as Assessed by M30 Expression in Keratoacanthoma and Squamous Cell Carcinoma
AutorTanja Batinac
AutorGordana Zamolo
AutorGordana Brumini
AutorDarko Biljan
AutorDuška Petranović
AutorBiserka Trošelj-Vukić
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za dermatovenerologiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za opću patologiju i patološku anatomiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Dermatovenerologija
Sažetak (engleski)
Involution displayed by keratoacanthoma (KA) represents an important difference between KA and squamous cell carcinoma (SCC). It has been suggested that apoptosis plays a part in process of involution of KA. Altogether 150 specimens were included in this study, 30 cases of each; normal skin (NS), proliferative (pKA) and regressing keratoacanthoma (rKA), well differentiated (wdSCC) and poorly differentiated (pdSCC) squamous cell carcinoma. All samples were examined immunohistochemicaly for expression of M30 protein. A significantly lower number of M30 positive cells has been detected in NS as compared to skin tumors examined (p<0.001), except for rKA (p=0.057). The highest percentage of M30 positive cells was detected in pdSCC (p<0.001) as compared with all other examined groups. Keratinocytes of normal and changed epidermis expressing higher levels of M30 protein were predominately found in sun-exposed areas (c 2=14.93; p=0.060). There was an increasing trend of M30 protein expression with increasing age of the patient in NS and skin tumors examined. Majority of skin tumors with higher percentage of M30 positive cells tended to display higher Ki-67 expression. M30 expression was highly correlated with bak (r=0.811; p=0.048) and granzyme B expression in rKA (r=0.733; p=0.015). Cell apoptosis as assessed by M30 expression is, generally, increased in examined skin tumors and related to cell proliferation. Cell apoptosis mediated by bak and granzyme B expression could contribute to KA regression.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCollegium antropologicum
Brojčani podacivol. 32, br. 2, str. 499-504
p-ISSN0350-6134
URN:NBNurn:nbn:hr:184:809787
Datum objave publikacije2008-07-07
URL dokumentahttp://hrcak.srce.hr/27217
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2017-09-17 19:08:32