Pelvic inflammatory disease (PID) is an infection of the female reproductive organs. It usually occurs when sexually transmitted bacteria spread from vagina to uterus, fallopian tubes or ovaries. Most of the time, PID is caused by bacteria from chlamydia and gonorrhea. Many women who develop pelvic inflammatory disease either experience no signs or symptoms or don't seek treatment. Pelvic inflammatory disease may be detected only later when women have trouble getting pregnant or if develop chronic pelvic pain. Common symptoms of PID include: pain or tenderness in the pelvis, lower belly, or lower back and fluid from vagina that has an unusual color, texture, or smell. Of other symptoms may occur: irregular bleeding, painful sex and pianful urination. Diagnosis includes: pelvic exam, blood tests, cervical culture, urine test, ultrasound, endometrial biopsy and laparoscopy. Treatment requires broad antimicrobial coverage against the likely pathogens, including Neisseria gonorrhoeae and Chlamydia trachomatis, and the gram – negative and gram – positive organisms that comprise the cervical and vaginal flora. Treatment can be inpatient or outpatient. Transitioning from parenteral to oral therapy can be started after 24 hours of sustained clinical improvement. The optimal duration of therapy is unknown, although it is considered that the period of 14 days is the best.Possible complications includes; chronic pelvic pain, ectopic pregnancy, infertility and tubo- ovarian abscess.