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Inositols in the Treatment of Polycystic Ovary Syndrome in Reproductive Age
U: Polycystic Ovary Syndrome - Symptoms, Causes and Treatment / Wang, Zhengchao (ur.). London: IntechOpen, 2024. str. 1-12. https://doi.org/10.5772/intechopen.113150
Smiljan Severinski, Neda; Marton, Ulla; Radojčić Badovinac, Anđelka

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Smiljan Severinski, N., Marton, U. i Radojčić Badovinac, A. (2024). Inositols in the Treatment of Polycystic Ovary Syndrome in Reproductive Age. U Z. Wang, (Ur.), Polycystic Ovary Syndrome - Symptoms, Causes and Treatment (str. 1-12). London: IntechOpen. doi: 10.5772/intechopen.113150

Smiljan Severinski, Neda, et al. "Inositols in the Treatment of Polycystic Ovary Syndrome in Reproductive Age." Polycystic Ovary Syndrome - Symptoms, Causes and Treatment, Ur. Zhengchao Wang, IntechOpen, 2024, str. 1-12. https://urn.nsk.hr/urn:nbn:hr:184:684603

Smiljan Severinski, Neda, Ulla Marton i Anđelka Radojčić Badovinac. "Inositols in the Treatment of Polycystic Ovary Syndrome in Reproductive Age." U Polycystic Ovary Syndrome - Symptoms, Causes and Treatment, ur. Zhengchao Wang, 1-12. London: IntechOpen, 2024. https://urn.nsk.hr/urn:nbn:hr:184:684603

Smiljan Severinski, N., Marton, U. i Radojčić Badovinac, A. (2024) 'Inositols in the Treatment of Polycystic Ovary Syndrome in Reproductive Age' u Wang, Z. (ur.) Polycystic Ovary Syndrome - Symptoms, Causes and Treatment London: IntechOpen, str. 1-12. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:184:684603 (Datum pristupa: 13.01.2025.)

Smiljan Severinski N, Marton U, Radojčić Badovinac A. Inositols in the Treatment of Polycystic Ovary Syndrome in Reproductive Age. U: Z. Wang, ur. Polycystic Ovary Syndrome - Symptoms, Causes and Treatment. London: IntechOpen; 2024. Str. 1-12. [pristupljeno 13.01.2025.] Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:684603

N. Smiljan Severinski, U. Marton i A. Radojčić Badovinac, "Inositols in the Treatment of Polycystic Ovary Syndrome in Reproductive Age", Polycystic Ovary Syndrome - Symptoms, Causes and Treatment, Z. Wang, Ur. London: IntechOpen, 2024, str. 1-12. [Online] Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:684603

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Podaci o radu
Naslov (engleski)Inositols in the Treatment of Polycystic Ovary Syndrome in Reproductive Age
AutorNeda Smiljan Severinski
AutorUlla Marton
AutorAnđelka Radojčić Badovinac
UrednikZhengchao Wang
Autorova ustanovaSveučilište u Rijeci
(Fakultet biotehnologije i razvoja lijekova)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za ginekologiju i opstetriciju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Ginekologija i opstetricija
Sažetak (engleski)
Polycystic ovary is part of an endocrine syndrome in which different pathophysiological mechanisms lead to a similar reproductive outcome: anovulation, irregularity of the menstrual cycle, and infertility. Hormonal and metabolic disorders are associated with reproductive adverse outcomes, which represent a vicious circle with dysfunctional ovaries. Hyperandrogenemia, disorder of carbohydrate metabolism, and sex hormone synthesis led to reproductive abnormalities. One of the most crucial questions still remains, whether the polycystic ovary is the cause or the consequence of all known disorders. Inositols are in the treatment of PCOS capable of restoring ovulation with the impact on the carbohydrate metabolism, by increasing the sensitivity of cells to insulin, which releases the sex hormones-binding protein and improves hyperandrogenemia. Nine stereoisomers of inositol are known, myo-inositol and chiro-inositol are the most studied in the reproductive age. By normalizing the level of androgens in the blood, the growth of and the balance of sex hormones is established. A variety of metabolic pathways of these molecules are recognized in different tissues, such as fat, muscle, or ovarian tissue. Still, it is not clear which isomer has better reproductive or metabolic effects, and there are controversies about their effectiveness in the treatment of reproductive disorders.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Poglavlje u knjizi
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov knjigePolycystic Ovary Syndrome - Symptoms, Causes and Treatment
Brojčani podacistr. 1-12, 113150
ISBN978-0-85014-143-6
DOIhttps://doi.org/10.5772/intechopen.113150
URN:NBNurn:nbn:hr:184:684603
Datum objave publikacije2024-06-19
ProjektŠifra: uniri-biomed-18-161
Naziv (hrvatski): Ekstracelularne vezikule humane folikularne tekućine: sadržaj i uloga u sazrijevanju oocite i kvaliteti embrija
Voditelj: Anđelka Radojčić-Badovinac
Pravna nadležnost: Hrvatska
Financijer: Sveučilište u Rijeci
URL dokumentahttps://www.intechopen.com/chapters/88333
Vrsta resursaTekst
IzdavačIntechOpen
Mjesto izdavanjaLondon
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 3.0 (CC BY 3.0)
Datum i vrijeme pohrane2024-11-29 13:36:44