prikaz prve stranice dokumenta Secondary polycythemia in acutely ill COVID-19 patients is associated with higher mortality but not markedly higher thrombotic risk
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Secondary polycythemia in acutely ill COVID-19 patients is associated with higher mortality but not markedly higher thrombotic risk
Scandinavian Journal of Clinical and Laboratory Investigation, 27 (2024); 1-7. https://doi.org/10.1080/00365513.2024.2321589
Lucijanić, Marko; Krečak, Ivan; Sorić, Ena; Sabljić, Anica; Vasilj, Tamara; Cicic, David; Vrkljan Vuk, Anamarija; Kremer, Zvonimir; Dilber, Ivo; Glasnović, Anton; Jakšić, Ozren; Kušec, Rajko

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Lucijanić, M., Krečak, I., Sorić, E., Sabljić, A., Vasilj, T., Cicic, D. ... Kušec, R. (2024). Secondary polycythemia in acutely ill COVID-19 patients is associated with higher mortality but not markedly higher thrombotic risk. Scandinavian Journal of Clinical and Laboratory Investigation, 27., 1-7. doi: 10.1080/00365513.2024.2321589

Lucijanić, Marko, et al. "Secondary polycythemia in acutely ill COVID-19 patients is associated with higher mortality but not markedly higher thrombotic risk." Scandinavian Journal of Clinical and Laboratory Investigation, vol. 27, 2024, str. 1-7. https://doi.org/10.1080/00365513.2024.2321589

Lucijanić, Marko, Ivan Krečak, Ena Sorić, Anica Sabljić, Tamara Vasilj, David Cicic, Anamarija Vrkljan Vuk, et al. "Secondary polycythemia in acutely ill COVID-19 patients is associated with higher mortality but not markedly higher thrombotic risk." Scandinavian Journal of Clinical and Laboratory Investigation 27 (2024): 1-7. https://doi.org/10.1080/00365513.2024.2321589

Lucijanić, M., et al. (2024) 'Secondary polycythemia in acutely ill COVID-19 patients is associated with higher mortality but not markedly higher thrombotic risk', Scandinavian Journal of Clinical and Laboratory Investigation, 27, str. 1-7. doi: 10.1080/00365513.2024.2321589

Lucijanić M, Krečak I, Sorić E, Sabljić A, Vasilj T, Cicic D, i sur.. Secondary polycythemia in acutely ill COVID-19 patients is associated with higher mortality but not markedly higher thrombotic risk. Scandinavian Journal of Clinical and Laboratory Investigation [Internet]. 27.02.2024. [pristupljeno 04.12.2024.];27:1-7. doi: 10.1080/00365513.2024.2321589

M. Lucijanić, et al., "Secondary polycythemia in acutely ill COVID-19 patients is associated with higher mortality but not markedly higher thrombotic risk", Scandinavian Journal of Clinical and Laboratory Investigation, vol. 27, str. 1-7, Veljača 2024. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:905823. [Citirano: 04.12.2024.]

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Naslov (engleski)Secondary polycythemia in acutely ill COVID-19 patients is associated with higher mortality but not markedly higher thrombotic risk
AutorMarko Lucijanić
AutorIvan Krečak
AutorEna Sorić
AutorAnica Sabljić
AutorTamara Vasilj
AutorDavid Cicic
AutorAnamarija Vrkljan Vuk
AutorZvonimir Kremer
AutorIvo Dilber
AutorAnton Glasnović
AutorOzren Jakšić
AutorRajko Kušec
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za internu medicinu)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Secondary polycythemia is commonly observed among patients with chronic pulmonary diseases. However, its significance in the context of Coronavirus disease 2019 (COVID-19) is unknown. We retrospectively evaluated a total of 5872 hospitalized COVID-19 patients with mostly severe and critical symptoms, and without prior or subsequently diagnosed myeloproliferative neoplasm. Patients were stratified based on admission hemoglobin into four subgroups: anemia (hemoglobin <120 g/L for females and 130 g/L for males), normal hemoglobin, mild (hemoglobin 160-165 g/L for females and 165-185 g/L for males) and severe polycythemia (hemoglobin >165 g/L for females and >185 g/L for males). Among 5872 patients, a total of 158 (2.7%) had mild and 25 (0.4%) severe polycythemia. Polycythemia was significantly associated with higher respiratory and functional impairment, reduced plasma volume, higher serum osmolarity and comorbidity burden specific to the degree of polycythemia. Patients presenting with mild (odds ratio (OR) = 1.63, p = .003) and severe polycythemia (OR = 4.98, p < .001) had increased risk of death in comparison to patients with normal hemoglobin, whereas no significant associations with venous thromboembolism, arterial thrombosis nor major bleeding were observed. Anemia was associated with higher risk of death (OR = 1.42, p < .001), venous thromboembolism (OR = 1.34, p < .006) and major bleeding (OR = 2.27, p < .001) in comparison to normal hemoglobin. Associations of polycythemia and anemia with mortality diminished, and anemia with venous thromboembolism and major bleeding persisted, after multivariate adjustments for age, sex, comorbidities, COVID-19 severity and functional status. Secondary polycythemia in hospitalized COVID-19 patients without prior of subsequently diagnosed myeloproliferative neoplasm is rare and is associated with high mortality, increasing with degree of polycythemia, but not markedly higher thrombotic risk
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaScandinavian Journal of Clinical and Laboratory Investigation
Brojčani podacivol. 27, str. 1-7, 2321589
p-ISSN0036-5513
e-ISSN1502-7686
DOIhttps://doi.org/10.1080/00365513.2024.2321589
URN:NBNurn:nbn:hr:184:905823
Datum objave publikacije2024-02-27
URL dokumentahttps://www.tandfonline.com/doi/full/10.1080/00365513.2024.2321589
Vrsta resursaTekst
Prava pristupaZatvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-04-08 11:47:21