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Sodium-Glucose Co-Transporter 2 Inhibitors as a Powerful Cardioprotective and Renoprotective Tool: Overview of Clinical Trials and Mechanisms
Diabetology, 4 (2023), 3; 251-258. https://doi.org/10.3390/diabetology4030022
Belančić, Andrej; Klobučar, Sanja

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Belančić, A. i Klobučar, S. (2023). Sodium-Glucose Co-Transporter 2 Inhibitors as a Powerful Cardioprotective and Renoprotective Tool: Overview of Clinical Trials and Mechanisms. Diabetology, 4. (3), 251-258. doi: 10.3390/diabetology4030022

Belančić, Andrej i Sanja Klobučar. "Sodium-Glucose Co-Transporter 2 Inhibitors as a Powerful Cardioprotective and Renoprotective Tool: Overview of Clinical Trials and Mechanisms." Diabetology, vol. 4, br. 3, 2023, str. 251-258. https://doi.org/10.3390/diabetology4030022

Belančić, Andrej i Sanja Klobučar. "Sodium-Glucose Co-Transporter 2 Inhibitors as a Powerful Cardioprotective and Renoprotective Tool: Overview of Clinical Trials and Mechanisms." Diabetology 4, br. 3 (2023): 251-258. https://doi.org/10.3390/diabetology4030022

Belančić, A. i Klobučar, S. (2023) 'Sodium-Glucose Co-Transporter 2 Inhibitors as a Powerful Cardioprotective and Renoprotective Tool: Overview of Clinical Trials and Mechanisms', Diabetology, 4(3), str. 251-258. doi: 10.3390/diabetology4030022

Belančić A, Klobučar S. Sodium-Glucose Co-Transporter 2 Inhibitors as a Powerful Cardioprotective and Renoprotective Tool: Overview of Clinical Trials and Mechanisms. Diabetology [Internet]. 04.07.2023. [pristupljeno 25.12.2024.];4(3):251-258. doi: 10.3390/diabetology4030022

A. Belančić i S. Klobučar, "Sodium-Glucose Co-Transporter 2 Inhibitors as a Powerful Cardioprotective and Renoprotective Tool: Overview of Clinical Trials and Mechanisms", Diabetology, vol. 4, br. 3, str. 251-258, Srpanj 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:874312. [Citirano: 25.12.2024.]

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Podaci o radu
Naslov (engleski)Sodium-Glucose Co-Transporter 2 Inhibitors as a Powerful Cardioprotective and Renoprotective Tool: Overview of Clinical Trials and Mechanisms
AutorAndrej Belančić
AutorSanja Klobučar
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za internu medicinu)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Sodium-glucose co-transporter 2 (SGLT2) inhibitors have been linked to beneficial effects on cardiovascular risk factors, blood pressure, body weight, and lipid profile, according to a substantial body of literature. Significant cardiac and renal benefits with the use of SGLT2 inhibitors have been shown in patients with type 2 diabetes, as well as in those with heart failure and/or chronic kidney disease (CKD), regardless of diabetes status, in subsequent large cardiovascular outcome trials. Thus, SGLT2 inhibitors have become a mainstay of therapy for type 2 diabetes in patients with established cardiovascular disease and CKD due to their benefits for the heart and kidneys. Based on data from randomized controlled trials and meta-analyses, this article attempts to present a thorough review of the mechanism of action, as well as the benefits of SGLT2 inhibitors for cardiac and renal protection. On the basis of a growing body of literature on diabetes and other conditions, clinical practice guidelines have been updated to suggest the use of SGLT2 inhibitors in specific patient populations. These modifications will also be concisely described, based on evidence-based medicine principles.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Ostalo
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaDiabetology
Brojčani podacivol. 4, br. 3, str. 251-258
e-ISSN2673-4540
DOIhttps://doi.org/10.3390/diabetology4030022
URN:NBNurn:nbn:hr:184:874312
Datum objave publikacije2023-07-04
URL dokumentahttps://www.mdpi.com/2673-4540/4/3/22
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2023-07-10 12:52:28