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The Significance of Heat-Shock Protein GP96 and its Receptors' CD91 and Toll-Like Receptor 4 Expression at the Maternal Foetal Interface
American Journal of Reproductive Immunology, 70 (2013), 1; 10-23. https://doi.org/10.1111/aji.12096
Gulić, Tamara; Laškarin, Gordana; Redžovic, Arnela; Eminović, Senija; Haller, Herman; Rukavina, Daniel

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Gulić, T., Laškarin, G., Redžovic, A., Eminović, S., Haller, H. i Rukavina, D. (2013). The Significance of Heat-Shock Protein GP96 and its Receptors' CD91 and Toll-Like Receptor 4 Expression at the Maternal Foetal Interface. American Journal of Reproductive Immunology, 70. (1), 10-23. doi: 10.1111/aji.12096

Gulić, Tamara, et al. "The Significance of Heat-Shock Protein GP96 and its Receptors' CD91 and Toll-Like Receptor 4 Expression at the Maternal Foetal Interface." American Journal of Reproductive Immunology, vol. 70, br. 1, 2013, str. 10-23. https://doi.org/10.1111/aji.12096

Gulić, Tamara, Gordana Laškarin, Arnela Redžovic, Senija Eminović, Herman Haller i Daniel Rukavina. "The Significance of Heat-Shock Protein GP96 and its Receptors' CD91 and Toll-Like Receptor 4 Expression at the Maternal Foetal Interface." American Journal of Reproductive Immunology 70, br. 1 (2013): 10-23. https://doi.org/10.1111/aji.12096

Gulić, T., et al. (2013) 'The Significance of Heat-Shock Protein GP96 and its Receptors' CD91 and Toll-Like Receptor 4 Expression at the Maternal Foetal Interface', American Journal of Reproductive Immunology, 70(1), str. 10-23. doi: 10.1111/aji.12096

Gulić T, Laškarin G, Redžovic A, Eminović S, Haller H, Rukavina D. The Significance of Heat-Shock Protein GP96 and its Receptors' CD91 and Toll-Like Receptor 4 Expression at the Maternal Foetal Interface. American Journal of Reproductive Immunology [Internet]. 07.2013. [pristupljeno 12.11.2024.];70(1):10-23. doi: 10.1111/aji.12096

T. Gulić, G. Laškarin, A. Redžovic, S. Eminović, H. Haller i D. Rukavina, "The Significance of Heat-Shock Protein GP96 and its Receptors' CD91 and Toll-Like Receptor 4 Expression at the Maternal Foetal Interface", American Journal of Reproductive Immunology, vol. 70, br. 1, str. 10-23, Srpanj 2013. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:654113. [Citirano: 12.11.2024.]

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Naslov (engleski)The Significance of Heat-Shock Protein GP96 and its Receptors' CD91 and Toll-Like Receptor 4 Expression at the Maternal Foetal Interface
AutorTamara Gulić
AutorGordana Laškarin
AutorArnela Redžovic
AutorSenija Eminović
AutorHerman Haller
AutorDaniel Rukavina
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za opću patologiju i patološku anatomiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Imunologija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Ginekologija i opstetricija
Sažetak (engleski)
Problem: Differences in the expression of gp96 and its receptors were analysed in normal and pathological human pregnancy. Material and Methods: Immunohistology and immunofluorescence of sections from decidual part of term placenta, first trimester normal decidua, missed abortion and blighted ovum decidua were performed together with reverse transcriptase-quantitative polymerase chain reaction and flow cytometry. Results: In missed abortion, gp96 was intensively stained, when compared to normal early pregnancy. The intensity of CD91 and TLR4 was higher in the first trimester pregnancy and blighted ovum, when compared to missed abortion. Decidual part of the term placenta is invaded with gp96+, CD91+ and TLR4+ trophoblast. Progesterone-induced blocking factor (PIBF) decreased the frequency of TLR4+ T lymphocytes, CD91+ T, natural killer (NK) and mature dendritic cells after an 18-h culture. Decidual mononuclear cells (DMCs) treated with PIBF down-regulated CD91, TLR4 and gp96 gene expression. Conclusion: The presence of gp96, CD91 and TLR4 at the maternal-foetal interface provides a molecular basis for their interaction, particularly in the absence of PIBF.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaAmerican Journal of Reproductive Immunology
Brojčani podacivol. 70, br. 1, str. 10-23
p-ISSN1046-7408
DOIhttps://doi.org/10.1111/aji.12096
URN:NBNurn:nbn:hr:184:654113
Datum objave publikacije2013-07
URL dokumentahttps://onlinelibrary.wiley.com/doi/10.1111/aji.12096
Vrsta resursaTekst
Prava pristupaOgraničen pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2023-06-30 08:09:08