prikaz prve stranice dokumenta Mystery Story about Erythropoietin (Epo) and Erythropoietin Receptor (EpoR) are Disguised?
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Mystery Story about Erythropoietin (Epo) and Erythropoietin Receptor (EpoR) are Disguised?
HEPATO-GASTROENTEROLOGY, 62 (2015), 139; 585-589. https://doi.org/10.5754/hge15033a
Čubranic, Aleksandar; Redžović, Arnela; Dobrila-Dintinjana, Renata; Vukelić, Jelena; Dintinjana, Marijan

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Čubranic, A., Redžović, A., Dobrila Dintinjana, R., Vukelić, J. i Dintinjana, M. (2015). Mystery Story about Erythropoietin (Epo) and Erythropoietin Receptor (EpoR) are Disguised?. HEPATO-GASTROENTEROLOGY, 62. (139), 585-589. doi: 10.5754/hge15033a

Čubranic, Aleksandar, et al. "Mystery Story about Erythropoietin (Epo) and Erythropoietin Receptor (EpoR) are Disguised?." HEPATO-GASTROENTEROLOGY, vol. 62, br. 139, 2015, str. 585-589. https://doi.org/10.5754/hge15033a

Čubranic, Aleksandar, Arnela Redžović, Renata Dobrila Dintinjana, Jelena Vukelić i Marijan Dintinjana. "Mystery Story about Erythropoietin (Epo) and Erythropoietin Receptor (EpoR) are Disguised?." HEPATO-GASTROENTEROLOGY 62, br. 139 (2015): 585-589. https://doi.org/10.5754/hge15033a

Čubranic, A., et al. (2015) 'Mystery Story about Erythropoietin (Epo) and Erythropoietin Receptor (EpoR) are Disguised?', HEPATO-GASTROENTEROLOGY, 62(139), str. 585-589. doi: 10.5754/hge15033a

Čubranic A, Redžović A, Dobrila Dintinjana R, Vukelić J, Dintinjana M. Mystery Story about Erythropoietin (Epo) and Erythropoietin Receptor (EpoR) are Disguised?. HEPATO-GASTROENTEROLOGY [Internet]. 2015. [pristupljeno 12.11.2024.];62(139):585-589. doi: 10.5754/hge15033a

A. Čubranic, A. Redžović, R. Dobrila Dintinjana, J. Vukelić i M. Dintinjana, "Mystery Story about Erythropoietin (Epo) and Erythropoietin Receptor (EpoR) are Disguised?", HEPATO-GASTROENTEROLOGY, vol. 62, br. 139, str. 585-589, 2015. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:074028. [Citirano: 12.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:074028
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Naslov (engleski)Mystery Story about Erythropoietin (Epo) and Erythropoietin Receptor (EpoR) are Disguised?
AutorAleksandar Čubranic
AutorArnela Redžović
AutorRenata Dobrila-Dintinjana
AutorJelena Vukelić
MBZ: 292473
AutorMarijan Dintinjana
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za onkologiju i radioterapiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
In this review we would like to focus our attention upon very controversial reports on Erythropoietin (Epo) and Erythropoietin Receptor (EpoR) expression in cancer patients. The effects of Epo on cancerous tissues are poorly understood. Hypoxia results in an increase in the level of the production of both Epo and EpoR via activation of the hypoxia- inducible factor 1 (HIF-1) pathway. HIF-1 alpha, promotes the expression of vascular endothelial growth factor (VEGF). The signaling through VEGF in both a paracrine and an autocrine manner is required for the homeostasis of adult vessels. Macrophages stimulate vessel sprouting via a soluble factor other than VEGF, rather than through direct contact with endothelial cells. The intriguing questions are set about many researches to link Epo/EpoR expression and function in order to establish one of the mechanisms of tumor growth, disease progression of cancer patient. However, it is uncertain role in tumour angiogenesis as promoter and stimulator of tumour growth which should need to be furtherly validated.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaHEPATO-GASTROENTEROLOGY
Brojčani podacivol. 62, br. 139, str. 585-589
p-ISSN0172-6390
DOIhttps://doi.org/10.5754/hge15033a
URN:NBNurn:nbn:hr:184:074028
Datum objave publikacije2015
URL dokumentahttp://bib.irb.hr/998053
Vrsta resursaTekst
Prava pristupaZatvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2023-06-30 07:54:32