Acute bronchiolitis is a seasonal respiratory tract infection which is the leading cause of hospitalization of children under the age of two, posing the largest risk to those prematurely born, with congenital cardiopulmonary diseases or immunocompromised. (5) This risk group should receive palivizumab during RSV season to a prevent severe course of disease. (5) Although the symptoms can occasionally origin from a bacterial infection, most commonly their cause is viral, most frequently RSV. (3) The diagnosis is made based on the clinical picture, which consists of first upper and later on lower respiratory tract infection symptoms. 30% of previously healthy children experience recurrent episodes of wheezing throughout the first decade of life. (2) The clinical course of the infection can be mild-moderate or severe. (5) In the former case, supportive outpatient care with fluids, antipyretic medications and nebulized saline is sufficient, as long as the symptoms do not worsen or red flags occur. (6) The later course of infection commonly requires hospitalization to administer equal supportive treatment, oxygen supplementation and close monitoring of the vital signs, fluid balance and respiration. (5) In cases of severe respiratory distress, mechanical ventilation, CPAP or HFNC may be necessary. (2) Many medications have been discussed and considered to treat the first episode of viral bronchiolitis in previously healthy children, but none can be recommended for routine use. In children at risk for severe disease, ribavirin can be considered (7) and chest physiotherapy should be performed if comorbidities impeding clearance of respiratory secretions are present. (2) Antibiotics may be prescribed only if a bacterial coinfection is present. (6)