prikaz prve stranice dokumenta MCMV induces activation and accumulation of Arf6 GTPase on membranes of virion assembly compartment
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Izlaganje na skupu
MCMV induces activation and accumulation of Arf6 GTPase on membranes of virion assembly compartment
Na: 2021 Annual Meeting of the Croatian Immunological Society. Trogir, Hrvatska, 2021. urn:nbn:hr:184:924123
Pavišić, Valentino; Mahmutefendić Lučin, Hana; Gulić, Tamara; Jug Vučko, Natalia; Lučin, Pero; Blagojević Zagorac, Gordana

Citirajte ovaj rad

Pavišić, V., Mahmutefendić Lučin, H., Gulić, T., Jug Vučko, N., Lučin, P. i Blagojević Zagorac, G. MCMV induces activation and accumulation of Arf6 GTPase on membranes of virion assembly compartment [PowerPoint prezentacija]. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:184:924123

Pavišić, Valentino, et al. "MCMV induces activation and accumulation of Arf6 GTPase on membranes of virion assembly compartment." 2021 Annual Meeting of the Croatian Immunological Society, 23.09.2021.-25.09.2021., Trogir, Hrvatska. Prezentacija. https://urn.nsk.hr/urn:nbn:hr:184:924123

Pavišić, Valentino, Hana Mahmutefendić Lučin, Tamara Gulić, Natalia Jug Vučko, Pero Lučin i Gordana Blagojević Zagorac. "MCMV induces activation and accumulation of Arf6 GTPase on membranes of virion assembly compartment." Prezentacija sa skupa 2021 Annual Meeting of the Croatian Immunological Society, Trogir, Hrvatska, 23.09.2021.-25.09.2021. https://urn.nsk.hr/urn:nbn:hr:184:924123

Pavišić, V., et al. 'MCMV induces activation and accumulation of Arf6 GTPase on membranes of virion assembly compartment' [Prezentacija], 2021 Annual Meeting of the Croatian Immunological Society. 23.09.2021.-25.09.2021. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:184:924123

Pavišić V, Mahmutefendić Lučin H, Gulić T, Jug Vučko N, Lučin P, Blagojević Zagorac G. MCMV induces activation and accumulation of Arf6 GTPase on membranes of virion assembly compartment. [Prezentacija] [pristupljeno 25.11.2024.] Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:924123

V. Pavišić, H. Mahmutefendić Lučin, T. Gulić, N. Jug Vučko, P. Lučin i G. Blagojević Zagorac, "MCMV induces activation and accumulation of Arf6 GTPase on membranes of virion assembly compartment", prezentirano na: 2021 Annual Meeting of the Croatian Immunological Society, Trogir, 23.09.2021.-25.09.2021. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:924123

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Podaci o radu
Naslov (engleski)MCMV induces activation and accumulation of Arf6 GTPase on membranes of virion assembly compartment
AutorValentino Pavišić
AutorHana Mahmutefendić Lučin
AutorTamara Gulić
AutorNatalia Jug Vučko
AutorPero Lučin
AutorGordana Blagojević Zagorac
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za fiziologiju, imunologiju i patofiziologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Sažetak (engleski)
Shortly after entering the host cells, murine cytomegaloviruses (MCMVs) reorganize Golgi and endosomal system of the infected cells and form the MCMV assembly compartment (AC) in order to enable production of the new virions. One of the features of the reorganized membrane organelles in AC is the extensive tubulation that in uninfected cells, among other GTPases from Ras family, is triggered by Arf GTPases, especially Arf6. The aim of this study was to determine expression, localization, as well as degree of activation of Arf6 and its main regulators (GAPs and GEFs) during MCMV infection. In order to address this question, Balb 3T3 cells were infected with recombinant murine cytomegalovirus Δm138-MCMV and expression of Arf6, its regulators, and MCMV viral proteins was followed up to 30 hours post infection (30 hpi) by Western blot and by confocal microscopy. Degree of Arf6 activation was determined by pull-down and wound healing assays. Viral replication was monitored in cells infected with C3X-GFP MCMV. Up to 30 hpi, there are no significant changes in Arf6 expression, although its intracellular localization and activation are altered by MCMV infection, as are the levels and intracellular localization of its major regulators.
Jezikengleski
Vrsta recenzijeNepoznato
URN:NBNurn:nbn:hr:184:924123
Datum izlaganja2021-09-23
ProjektŠifra: HRZZ-2020-2-1323
Naziv (hrvatski): Stanični sustav Arf GTPaza u patogenezi citomegalovirusne infekcije
Voditelj: Gordana Blagojević Zagorac
Pravna nadležnost: Hrvatska
Financijer: HRZZ
SkupNaziv: 2021 Annual Meeting of the Croatian Immunological Society
Kratica: HID
Lokacija: Trogir, Hrvatska
Organizator: HID
Datum početka: 2021-09-23
Datum završetka: 2021-09-25
Vrsta izlaganja: Predavanje
Vrsta resursaTekst
Prava pristupaOgraničen pristup
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Datum i vrijeme pohrane2023-04-05 08:00:59