prikaz prve stranice dokumenta Immunohistochemical and Histopathological Features of Persistent Gingival Enlargement in Relation to Metal Allergic Sensitisation during Orthodontic Treatment
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Immunohistochemical and Histopathological Features of Persistent Gingival Enlargement in Relation to Metal Allergic Sensitisation during Orthodontic Treatment
Materials, 16 (2023), 1; 81. https://doi.org/10.3390/ma16010081
Žigante, Martina; Špalj, Stjepan; Prpić, Jelena; Pavlić, Andrej; Katić, Višnja; Matušan Ilijaš, Koviljka

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Žigante, M., Špalj, S., Prpić, J., Pavlić, A., Katić, V. i Matušan Ilijaš, K. (2023). Immunohistochemical and Histopathological Features of Persistent Gingival Enlargement in Relation to Metal Allergic Sensitisation during Orthodontic Treatment. Materials, 16. (1). doi: 10.3390/ma16010081

Žigante, Martina, et al. "Immunohistochemical and Histopathological Features of Persistent Gingival Enlargement in Relation to Metal Allergic Sensitisation during Orthodontic Treatment." Materials, vol. 16, br. 1, 2023. https://doi.org/10.3390/ma16010081

Žigante, Martina, Stjepan Špalj, Jelena Prpić, Andrej Pavlić, Višnja Katić i Koviljka Matušan Ilijaš. "Immunohistochemical and Histopathological Features of Persistent Gingival Enlargement in Relation to Metal Allergic Sensitisation during Orthodontic Treatment." Materials 16, br. 1 (2023). https://doi.org/10.3390/ma16010081

Žigante, M., et al. (2023) 'Immunohistochemical and Histopathological Features of Persistent Gingival Enlargement in Relation to Metal Allergic Sensitisation during Orthodontic Treatment', Materials, 16(1). doi: 10.3390/ma16010081

Žigante M, Špalj S, Prpić J, Pavlić A, Katić V, Matušan Ilijaš K. Immunohistochemical and Histopathological Features of Persistent Gingival Enlargement in Relation to Metal Allergic Sensitisation during Orthodontic Treatment. Materials [Internet]. 2023. [pristupljeno 19.11.2024.];16(1). doi: 10.3390/ma16010081

M. Žigante, S. Špalj, J. Prpić, A. Pavlić, V. Katić i K. Matušan Ilijaš, "Immunohistochemical and Histopathological Features of Persistent Gingival Enlargement in Relation to Metal Allergic Sensitisation during Orthodontic Treatment", Materials, vol. 16, br. 1, 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:001972. [Citirano: 19.11.2024.]

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Naslov (engleski)Immunohistochemical and Histopathological Features of Persistent Gingival Enlargement in Relation to Metal Allergic Sensitisation during Orthodontic Treatment
AutorMartina Žigante
AutorStjepan Špalj
AutorJelena Prpić
AutorAndrej Pavlić
AutorVišnja Katić
AutorKoviljka Matušan Ilijaš
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za ortodonciju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Dentalna medicina
Ortodoncija
Sažetak (engleski)
This study aimed to analyse the immunohistochemical profile of inflammatory infiltrates in the gingival tissue of patients undergoing orthodontic treatment in relation to patients’ titanium and/or nickel allergy status. Patients with gingival enlargement received initial periodontal therapy, followed by external gingivectomy in the case of persistent gingival enlargement. The sample included 44 patients (22 had metal allergic sensitisation). Histopathological changes were assessed, and an immunohistochemical analysis was performed on formalin-fixed and paraffin-embedded gingival samples using antibodies against CD1a, CD3, CD4, CD8, CD20, CD68, and CD138. Computer-assisted image analysis was performed to evaluate the positive cell count in the gingival tissue. The gingiva of the sensitised patients was characterised by the absence of multifocal inflammatory infiltrates (p < 0.05), while pronounced exocytosis and band-like inflammatory infiltrates were more frequently observed in sensitised patients. In addition, there was an increase in Langerhans cells and T-helper lymphocytes and a decrease in naïve T-lymphocytes, cytotoxic T-lymphocytes, macrophages, and plasma cells in the sensitised subjects compared to non-sensitised. However, the differences were only statistically significant for macrophages, with a moderate effect size (82.8 vs. 133.9; p = 0.041; r = 0.308). The absence of multifocal inflammation appears to be the most characteristic histopathological feature of the gingiva of sensitised patients. Although their gingiva presented certain characteristics of late hypersensitivity immune reactions the observed changes imply dominant irritative effect e.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaMaterials
Brojčani podacivol. 16, br. 1, 81
e-ISSN1996-1944
DOIhttps://doi.org/10.3390/ma16010081
URN:NBNurn:nbn:hr:184:001972
Datum objave publikacije2023
ProjektŠifra: iP-2020-02-4027
Naziv (hrvatski): Okolišni čimbenici i mikrobiološke interakcije u strukturi dentalnog biofilma
Naziv (engleski): Environmental factors and microbiological interactions in the structure of dental biofilm
Kratica: DENTALBIOFILM
Voditelj: Stjepan Špalj
Pravna nadležnost: Hrvatska
Financijer: HRZZ
Linija financiranja: IP
ProjektŠifra: IP-2014-09-7500
Naziv (hrvatski): Imunosne i regenerativne implikacije korozije dentalnih materijala u djece i adolescenata
Naziv (engleski): Immunological and regenerative implications of corrosion of dental materials in children and adolescents
Kratica: IMUNODENT
Voditelj: Stjepan Špalj
Pravna nadležnost: Hrvatska
Financijer: HRZZ
Linija financiranja: IP
ProjektŠifra: DOK-2018-01-2531
Naziv (hrvatski): Imunosne i regenerativne implikacije korozije dentalnih materijala u djece i adolescenata
Voditelj: Stjepan Špalj
Pravna nadležnost: Hrvatska
Financijer: HRZZ
Linija financiranja: DOK
URL dokumentahttps://www.mdpi.com/1996-1944/16/1/81
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2023-01-10 13:11:48