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MASSIVE CLOZAPINE OVERDOSE: WHAT TO EXPECT?
Psychiatria Danubina, 32 (2020), 3-4; 431-433. https://doi.org/10.24869/psyd.2020.431
Erdeljić Turk, Viktorija; Kučan, Marta; Vitezić, Dinko

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Erdeljić Turk, V., Kučan, M. i Vitezić, D. (2020). MASSIVE CLOZAPINE OVERDOSE: WHAT TO EXPECT?. Psychiatria Danubina, 32. (3-4), 431-433. doi: 10.24869/psyd.2020.431

Erdeljić Turk, Viktorija, et al. "MASSIVE CLOZAPINE OVERDOSE: WHAT TO EXPECT?." Psychiatria Danubina, vol. 32, br. 3-4, 2020, str. 431-433. https://doi.org/10.24869/psyd.2020.431

Erdeljić Turk, Viktorija, Marta Kučan i Dinko Vitezić. "MASSIVE CLOZAPINE OVERDOSE: WHAT TO EXPECT?." Psychiatria Danubina 32, br. 3-4 (2020): 431-433. https://doi.org/10.24869/psyd.2020.431

Erdeljić Turk, V., Kučan, M. i Vitezić, D. (2020) 'MASSIVE CLOZAPINE OVERDOSE: WHAT TO EXPECT?', Psychiatria Danubina, 32(3-4), str. 431-433. doi: 10.24869/psyd.2020.431

Erdeljić Turk V, Kučan M, Vitezić D. MASSIVE CLOZAPINE OVERDOSE: WHAT TO EXPECT?. Psychiatria Danubina [Internet]. 24.12.2020. [pristupljeno 04.12.2024.];32(3-4):431-433. doi: 10.24869/psyd.2020.431

V. Erdeljić Turk, M. Kučan i D. Vitezić, "MASSIVE CLOZAPINE OVERDOSE: WHAT TO EXPECT?", Psychiatria Danubina, vol. 32, br. 3-4, str. 431-433, Prosinac 2020. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:412869. [Citirano: 04.12.2024.]

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Podaci o radu
Naslov (engleski)MASSIVE CLOZAPINE OVERDOSE: WHAT TO EXPECT?
AutorViktorija Erdeljić Turk
AutorMarta Kučan
AutorDinko Vitezić
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za farmakologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Klinička farmakologija s toksikologijom
Sažetak (engleski)
Clozapine is an atypical antipsychotic drug indicated for treatment-resistant schizophrenia. Despite its superior clinical efficacy, many deleterious adverse events, including agranulocytosis, have resulted in its more judicious use (Asenjo Lobos et al. 2010). The most frequently reported symptoms of clozapine intoxication are impaired alertness and tachycardia; other symptoms include: hyperthermia, alterations in consciousness, dysarthria, ataxia, seizures, cardiac arrhythmias, excessive bronchial mucus, hypersalivation, miosis, blood dyscrasias, pancreatitis and hepatitis (Le Blaye et al. 1992, Krämer et al. 2010). Studies that evaluated the case fatality rate with various antipsychotics concluded that clozapine was far more toxic than other antipsychotics (Ferrey 2018). To the best of our knowledge, this is the fist case report describing treatment and outcomes following a massive overdose of clozapine, amounting to 46.7 times the recommended patient’s daily dose of clozapine.
Jezikengleski
Vrsta publikacijeZnanstveni rad - Prikaz slučaja
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaPsychiatria Danubina
Brojčani podacivol. 32, br. 3-4, str. 431-433
p-ISSN0353-5053
DOIhttps://doi.org/10.24869/psyd.2020.431
URN:NBNurn:nbn:hr:184:412869
Datum objave publikacije2020-12-24
URL dokumentahttp://www.psychiatria-danubina.com/UserDocsImages/pdf/dnb_vol32_no3-4/dnb_vol32_no3-4_431.pdf
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-10-14 07:29:29