prikaz prve stranice dokumenta Improvement of endothelial function by pitavastatin: a meta-analysis
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Improvement of endothelial function by pitavastatin: a meta-analysis
Expert Opinion on Pharmacotherapy, 19 (2018), 3; 279-286. https://doi.org/10.1080/14656566.2018.1428560
Katsiki, Niki; Reiner, Željko; Tedeschi Reiner, Eugenia; Al-Rasadi, Khalid; Pirro, Matteo; Mikhailidis, Dimitri P.; Sahebkar, Amirhossein

Citirajte ovaj rad

Katsiki, N., Reiner, Ž., Tedeschi Reiner, E., Al Rasadi, K., Pirro, M., Mikhailidis, D. P. i Sahebkar, A. (2018). Improvement of endothelial function by pitavastatin: a meta-analysis. Expert Opinion on Pharmacotherapy, 19. (3), 279-286. doi: 10.1080/14656566.2018.1428560

Katsiki, Niki, et al. "Improvement of endothelial function by pitavastatin: a meta-analysis." Expert Opinion on Pharmacotherapy, vol. 19, br. 3, 2018, str. 279-286. https://doi.org/10.1080/14656566.2018.1428560

Katsiki, Niki, Željko Reiner, Eugenia Tedeschi Reiner, Khalid Al Rasadi, Matteo Pirro, Dimitri P. Mikhailidis i Amirhossein Sahebkar. "Improvement of endothelial function by pitavastatin: a meta-analysis." Expert Opinion on Pharmacotherapy 19, br. 3 (2018): 279-286. https://doi.org/10.1080/14656566.2018.1428560

Katsiki, N., et al. (2018) 'Improvement of endothelial function by pitavastatin: a meta-analysis', Expert Opinion on Pharmacotherapy, 19(3), str. 279-286. doi: 10.1080/14656566.2018.1428560

Katsiki N, Reiner Ž, Tedeschi Reiner E, Al Rasadi K, Pirro M, Mikhailidis DP, i sur.. Improvement of endothelial function by pitavastatin: a meta-analysis. Expert Opinion on Pharmacotherapy [Internet]. 2018. [pristupljeno 19.11.2024.];19(3):279-286. doi: 10.1080/14656566.2018.1428560

N. Katsiki, et al., "Improvement of endothelial function by pitavastatin: a meta-analysis", Expert Opinion on Pharmacotherapy, vol. 19, br. 3, str. 279-286, 2018. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:221405. [Citirano: 19.11.2024.]

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Naslov (engleski)Improvement of endothelial function by pitavastatin: a meta-analysis
AutorNiki Katsiki
AutorŽeljko Reiner
MBZ: 65232
AutorEugenia Tedeschi Reiner
MBZ: 152304
AutorKhalid Al-Rasadi
AutorMatteo Pirro
AutorDimitri P. Mikhailidis
AutorAmirhossein Sahebkar
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za internu medicinu)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Objective. Dyslipidemia is commonly associated with endothelial dysfunction and increased cardiovascular risk. Pitavastatin has been shown to reduce total and low-density lipoprotein cholesterol, to increase high- density lipoprotein (HDL)-cholesterol and improve HDL function. Furthermore, several trials explored its effects on flow-mediated dilation (FMD), as an index of endothelial function. The authors evaluated the effect of pitavastatin therapy on FMD.Methods. The authors performed a systematic review and meta- analysis of all clinical trials exploring the impact of pitavastatin on FMD. The search included PubMed-Medline, Scopus, ISI Web of Knowledge and Google Scholar databases. Quantitative data synthesis was performed using a random-effects model, with weighted mean difference (WMD) and 95% confidence interval (CI) as summary statistics.Results. Six eligible studies comprising 7 treatment arms were selected for this meta-analysis. Overall, WMD was significant for the effect of pitavastatin on FMD (2.45%, 95% CI: 1.31, 3.60, p<0.001) and the effect size was robust in the leave-one-out sensitivity analysis.Conclusion. This meta-analysis of all available clinical trials revealed a significant increase of FMD induced by pitavastatin
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeZavršna verzija rukopisa prihvaćena za objavljivanje (postprint)
Naslov časopisaExpert Opinion on Pharmacotherapy
Brojčani podacivol. 19, br. 3, str. 279-286
p-ISSN1465-6566
DOIhttps://doi.org/10.1080/14656566.2018.1428560
URN:NBNurn:nbn:hr:184:221405
Datum objave publikacije2018
URL dokumentahttp://bib.irb.hr/1050328
Vrsta resursaTekst
Prava pristupaOgraničen pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-02-22 17:31:32