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FGF2 Enhances Odontoblast Differentiation by αSMA Progenitors In Vivo
Journal of Dental Research, 97 (2018), 10; 1170-1177. https://doi.org/10.1177/0022034518769827
Vidović-Zdrilić, Ivana; Vining, K.H.; Vijaykumar, A.; Kalajzić, I.; Mooney, D.J.; Mina, M.

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Vidović Zdrilić, I., Vining, K., Vijaykumar, A., Kalajzić, I., Mooney, D. i Mina, M. (2018). FGF2 Enhances Odontoblast Differentiation by αSMA Progenitors In Vivo. Journal of Dental Research, 97. (10), 1170-1177. doi: 10.1177/0022034518769827

Vidović Zdrilić, Ivana, et al. "FGF2 Enhances Odontoblast Differentiation by αSMA Progenitors In Vivo." Journal of Dental Research, vol. 97, br. 10, 2018, str. 1170-1177. https://doi.org/10.1177/0022034518769827

Vidović Zdrilić, Ivana, K.H. Vining, A. Vijaykumar, I. Kalajzić, D.J. Mooney i M. Mina. "FGF2 Enhances Odontoblast Differentiation by αSMA Progenitors In Vivo." Journal of Dental Research 97, br. 10 (2018): 1170-1177. https://doi.org/10.1177/0022034518769827

Vidović Zdrilić, I., et al. (2018) 'FGF2 Enhances Odontoblast Differentiation by αSMA Progenitors In Vivo', Journal of Dental Research, 97(10), str. 1170-1177. doi: 10.1177/0022034518769827

Vidović Zdrilić I, Vining K, Vijaykumar A, Kalajzić I, Mooney D, Mina M. FGF2 Enhances Odontoblast Differentiation by αSMA Progenitors In Vivo. Journal of Dental Research [Internet]. 12.04.2018. [pristupljeno 03.12.2024.];97(10):1170-1177. doi: 10.1177/0022034518769827

I. Vidović Zdrilić, K. Vining, A. Vijaykumar, I. Kalajzić, D. Mooney i M. Mina, "FGF2 Enhances Odontoblast Differentiation by αSMA Progenitors In Vivo", Journal of Dental Research, vol. 97, br. 10, str. 1170-1177, Travanj 2018. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:713083. [Citirano: 03.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:713083
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Naslov (engleski)FGF2 Enhances Odontoblast Differentiation by αSMA Progenitors In Vivo
AutorIvana Vidović-Zdrilić
AutorK.H. Vining
AutorA. Vijaykumar
AutorI. Kalajzić
AutorD.J. Mooney
AutorM. Mina
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za endodonciju i restorativnu stomatologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Dentalna medicina
Endodoncija i restaurativna dentalna medicina
Sažetak (engleski)
The goal of this study was to examine the effects of early and limited exposure of perivascular cells expressing α (αSMA) to fibroblast growth factor 2 (FGF2) in vivo. We performed in vivo fate mapping by inducible Cre-loxP and experimental pulp injury in molars to induce reparative dentinogenesis. Our results demonstrate that early delivery of exogenous FGF2 to exposed pulp led to proliferative expansion of αSMA-tdTomato cells and their accelerated differentiation into odontoblasts. In vivo lineage-tracing experiments showed that the calcified bridge/reparative dentin in FGF2-treated pulps were lined with an increased number of Dspp odontoblasts and devoid of BSP osteoblasts. The increased number of odontoblasts derived from αSMA-tdTomato cells and the formation of reparative dentin devoid of osteoblasts provide in vivo evidence for the stimulatory effects of FGF signaling on odontoblast differentiation from early progenitors in dental pulp.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Dental Research
Brojčani podacivol. 97, br. 10, str. 1170-1177
p-ISSN0022-0345
e-ISSN1544-0591
DOIhttps://doi.org/10.1177/0022034518769827
URN:NBNurn:nbn:hr:184:713083
Datum objave publikacije2018-04-12
URL dokumentahttp://journals.sagepub.com/doi/10.1177/0022034518769827
Vrsta resursaTekst
Prava pristupaInstitucijski pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-02-21 13:36:24