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Assessment of the Biological Activity and Phenolic Composition of Ethanol Extracts of Pomegranate (Punica granatum L.) Peels
Molecules, 25 (2020), 24; 5916. https://doi.org/10.3390/molecules25245916
Peršurić, Željka; Saftić Martinović, Lara; Malenica, Mladenka; Gobin, Ivana; Pedisić, Sandra; Dragović-Uzelac, Verica; Kraljević Pavelić, Sandra

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Peršurić, Ž., Saftić Martinović, L., Malenica, M., Gobin, I., Pedisić, S., Dragović Uzelac, V. i Kraljević Pavelić, S. (2020). Assessment of the Biological Activity and Phenolic Composition of Ethanol Extracts of Pomegranate (Punica granatum L.) Peels. Molecules, 25. (24). doi: 10.3390/molecules25245916

Peršurić, Željka, et al. "Assessment of the Biological Activity and Phenolic Composition of Ethanol Extracts of Pomegranate (Punica granatum L.) Peels." Molecules, vol. 25, br. 24, 2020. https://doi.org/10.3390/molecules25245916

Peršurić, Željka, Lara Saftić Martinović, Mladenka Malenica, Ivana Gobin, Sandra Pedisić, Verica Dragović Uzelac i Sandra Kraljević Pavelić. "Assessment of the Biological Activity and Phenolic Composition of Ethanol Extracts of Pomegranate (Punica granatum L.) Peels." Molecules 25, br. 24 (2020). https://doi.org/10.3390/molecules25245916

Peršurić, Ž., et al. (2020) 'Assessment of the Biological Activity and Phenolic Composition of Ethanol Extracts of Pomegranate (Punica granatum L.) Peels', Molecules, 25(24). doi: 10.3390/molecules25245916

Peršurić Ž, Saftić Martinović L, Malenica M, Gobin I, Pedisić S, Dragović Uzelac V, i sur.. Assessment of the Biological Activity and Phenolic Composition of Ethanol Extracts of Pomegranate (Punica granatum L.) Peels. Molecules [Internet]. 14.12.2020. [pristupljeno 26.12.2024.];25(24). doi: 10.3390/molecules25245916

Ž. Peršurić, et al., "Assessment of the Biological Activity and Phenolic Composition of Ethanol Extracts of Pomegranate (Punica granatum L.) Peels", Molecules, vol. 25, br. 24, Prosinac 2020. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:947901. [Citirano: 26.12.2024.]

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Naslov (engleski)Assessment of the Biological Activity and Phenolic Composition of Ethanol Extracts of Pomegranate (Punica granatum L.) Peels
AutorŽeljka Peršurić
AutorLara Saftić Martinović
AutorMladenka Malenica
AutorIvana Gobin
AutorSandra Pedisić
AutorVerica Dragović-Uzelac
AutorSandra Kraljević Pavelić
Autorova ustanovaSveučilište u Rijeci
Fakultet zdravstvenih studija
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
Autorova ustanovaSveučilište u Rijeci
(Fakultet biotehnologije i razvoja lijekova)
Autorova ustanovaSveučilište u Zagrebu
Prehrambeno-biotehnološki fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOTEHNIČKE ZNANOSTI
Prehrambena tehnologija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Medicinska mikrobiologija
Sažetak (engleski)
Pomegranate (Punica granatum L.) is a rich source of constituents with confirmed strong biological activities. However, pomegranate peel, which encompasses approximately 30–40% of its weight, is treated as a biological waste. The aim of this paper was to evaluate the potential of pomegranate peel extracts and to propose its functional properties that can be used for development of functional products. Eight ethanol extracts of pomegranate peels (PPEs) were characterized by use of direct infusion quadrupole-time of flight (Q-TOF), and afterwards tested on their antioxidant, antibacterial and antiproliferative activities. Mass spectrometry analysis revealed that the most prevalent compounds in pomegranate peels were punicalagin, granatin and their derivatives. Analysed extracts had high total phenolic contents that ranged from 5766.44 to 10599.43 mg GAE/100 g, and strong antioxidant activity (7551.31–7875.42 and 100.25–176.60 μmol TE/100 g for DPPH and FRAP assays, respectively). The results of biological activity assays showed that all PPEs possessed antibacterial activity, and that S. aureus was the most sensitive specie with minimum inhibitory concentration and minimum bactericidal concentrations ranging from 0.8 to 6.4 mg/mL. Additionally, the analysis of antiproliferative activity revealed high potency of PPEs, as the IC50 values ranged from 0.132 mg/mL to 0.396 mg/mL. Multivariate analysis pointed out the most discriminative metabolites for antioxidant or antiproliferative activity. Overall, the pomegranate peel confirmed to be a highly valuable source of bioactive compounds that could be used to improve the food functional characteristics.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaMolecules
Brojčani podacivol. 25, br. 24, 5916
e-ISSN1420-3049
DOIhttps://doi.org/10.3390/molecules25245916
URN:NBNurn:nbn:hr:184:947901
Datum objave publikacije2020-12-14
URL dokumentahttps://www.mdpi.com/1420-3049/25/24/5916
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2021-01-04 13:19:39