Liver diseases in pregnancy occurs in about 3-5% of pregnant women and are associated with significant risk for mother and fetus mortality. They are devided into those occurring in the first trimester (such as hyperemesis gravidarum) and those occurring in second and third trimester (acute fat liver atrophy of pregnancy, preeclampsia, HELLP syndrome etc.). Because of unspecific symptoms they can be easily replaced with other liver diseases, that occur independently of pregnancy. Liver diseases that are unspecific for pregnancy, may occurr „de novo“ in pregnancy or patient may have liver pathology prior to pregnancy. For early and high quality therapy, it is important to distinguish whether the liver disease is specific or not specific to pregnancy. Only in this way, we can avoid additional side effects and drug contraindications, which can endanger the heatlh of the mother and the fetus. This review deals with the risk factors, diagnostic protocols and therapeutic options for liver diseases in pregnancy. Because of the complex nature of these diseases, there are some disagreements among scientists on therapy. However, due to progress in the field of feto maternal medicine, mortality rate have been significantly reduce.