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MONOCLONAL ANTIBODIES REACTIVE WITH SWINE LYMPHOCYTES II. Detection of an Antigen on Resting T Cells Down-Regulated After Activation
Journal of Immunology, 138 (1987), 6; 1852-1857. urn:nbn:hr:184:924665
Saalmüller, Armin; Jonjić, Stipan; Bühring, Hans-Jörg; Reddehase, Matthias J.; Koszinowski, Ulrich H.

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Saalmüller, A., Jonjić, S., Bühring, H. J., Reddehase, M. J. i Koszinowski, U. H. (1987). MONOCLONAL ANTIBODIES REACTIVE WITH SWINE LYMPHOCYTES II. Detection of an Antigen on Resting T Cells Down-Regulated After Activation. Journal of Immunology, 138. (6), 1852-1857. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:184:924665

Saalmüller, Armin, et al. "MONOCLONAL ANTIBODIES REACTIVE WITH SWINE LYMPHOCYTES II. Detection of an Antigen on Resting T Cells Down-Regulated After Activation." Journal of Immunology, vol. 138, br. 6, 1987, str. 1852-1857. https://urn.nsk.hr/urn:nbn:hr:184:924665

Saalmüller, Armin, Stipan Jonjić, Hans Jörg Bühring, Matthias J. Reddehase i Ulrich H. Koszinowski. "MONOCLONAL ANTIBODIES REACTIVE WITH SWINE LYMPHOCYTES II. Detection of an Antigen on Resting T Cells Down-Regulated After Activation." Journal of Immunology 138, br. 6 (1987): 1852-1857. https://urn.nsk.hr/urn:nbn:hr:184:924665

Saalmüller, A., et al. (1987) 'MONOCLONAL ANTIBODIES REACTIVE WITH SWINE LYMPHOCYTES II. Detection of an Antigen on Resting T Cells Down-Regulated After Activation', Journal of Immunology, 138(6), str. 1852-1857. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:184:924665 (Datum pristupa: 21.01.2025.)

Saalmüller A, Jonjić S, Bühring HJ, Reddehase MJ, Koszinowski UH. MONOCLONAL ANTIBODIES REACTIVE WITH SWINE LYMPHOCYTES II. Detection of an Antigen on Resting T Cells Down-Regulated After Activation. Journal of Immunology [Internet]. 1987. [pristupljeno 21.01.2025.];138(6):1852-1857. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:924665

A. Saalmüller, S. Jonjić, H. J. Bühring, M. J. Reddehase i U. H. Koszinowski, "MONOCLONAL ANTIBODIES REACTIVE WITH SWINE LYMPHOCYTES II. Detection of an Antigen on Resting T Cells Down-Regulated After Activation", Journal of Immunology, vol. 138, br. 6, str. 1852-1857, 1987. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:924665. [Citirano: 21.01.2025.]

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Naslov (engleski)MONOCLONAL ANTIBODIES REACTIVE WITH SWINE LYMPHOCYTES II. Detection of an Antigen on Resting T Cells Down-Regulated After Activation
AutorArmin Saalmüller
AutorStipan Jonjić
AutorHans-Jörg Bühring
AutorMatthias J. Reddehase
AutorUlrich H. Koszinowski
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za histologiju i embriologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Sažetak (engleski)
The expression of an antigen on porcine T lymphocytes detected by murine monoclonal antibody (mAb) 8/1 was investigated by functional studies and dual-parameter immunofluorescence. mAb 8/1 reacts with greater than 95% of thymocytes and in peripheral blood with all T lymphocytes and with cells of the monocyte/macrophage lineage, but not with B cells, erythrocytes, and platelets. Pretreatment of peripheral blood lymphocytes with mAb 8/1 plus complement abrogated the proliferative response in vitro to mitogen, soluble antigen, and MHC determinants. Dual-parameter immunofluorescence revealed that resting porcine T8+ as well as T4+ lymphocytes express the 8/1 antigen, whereas after in vitro activation, cell surface expression of the antigen was low or absent in both T cell subsets. Thus, the 8/1 antigen represents a marker that discriminates between resting and activated T lymphocytes. Distribution and functional criteria indicate that 8/1 represents a novel marker not described before for any other mammalian species.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Immunology
Brojčani podacivol. 138, br. 6, str. 1852-1857
p-ISSN0022-1767
e-ISSN1550-6606
URN:NBNurn:nbn:hr:184:924665
Datum objave publikacije1987
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno 4.0 međunarodna (CC BY-NC 4.0)
Datum i vrijeme pohrane2019-04-08 13:59:18