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MCMV avoidance of recognition and control by NK cells
Seminars in Immunopathology, 36 (2014), 6; 641-650. https://doi.org/10.1007/s00281-014-0441-9
Brizić, Ilija; Lenac Roviš, Tihana; Krmpotić, Astrid; Jonjić, Stipan

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Brizić, I., Lenac Roviš, T., Krmpotić, A. i Jonjić, S. (2014). MCMV avoidance of recognition and control by NK cells. Seminars in Immunopathology, 36. (6), 641-650. doi: 10.1007/s00281-014-0441-9

Brizić, Ilija, et al. "MCMV avoidance of recognition and control by NK cells." Seminars in Immunopathology, vol. 36, br. 6, 2014, str. 641-650. https://doi.org/10.1007/s00281-014-0441-9

Brizić, Ilija, Tihana Lenac Roviš, Astrid Krmpotić i Stipan Jonjić. "MCMV avoidance of recognition and control by NK cells." Seminars in Immunopathology 36, br. 6 (2014): 641-650. https://doi.org/10.1007/s00281-014-0441-9

Brizić, I., et al. (2014) 'MCMV avoidance of recognition and control by NK cells', Seminars in Immunopathology, 36(6), str. 641-650. doi: 10.1007/s00281-014-0441-9

Brizić I, Lenac Roviš T, Krmpotić A, Jonjić S. MCMV avoidance of recognition and control by NK cells. Seminars in Immunopathology [Internet]. 21.08.2014. [pristupljeno 26.12.2024.];36(6):641-650. doi: 10.1007/s00281-014-0441-9

I. Brizić, T. Lenac Roviš, A. Krmpotić i S. Jonjić, "MCMV avoidance of recognition and control by NK cells", Seminars in Immunopathology, vol. 36, br. 6, str. 641-650, Kolovoz 2014. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:853548. [Citirano: 26.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:853548
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Podaci o radu
Naslov (engleski)MCMV avoidance of recognition and control by NK cells
AutorIlija Brizić
AutorTihana Lenac Roviš
AutorAstrid Krmpotić
AutorStipan Jonjić
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Centar za proteomiku)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za histologiju i embriologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Sažetak (engleski)
Natural killer (NK) cells play an important role in virus control during infection. Many viruses have developed mechanisms for subversion of NK cell responses. Murine cytomegalovirus (MCMV) is exceptionally successful in avoiding NK cell control. Here, we summarize the major MCMV evasion mechanisms targeting NK cell functions and their role in viral pathogenesis. The mechanisms by which NK cells regulate CD8+ T cell response, particularly with respect to the role of NK cell receptors recognizing viral antigens, are discussed. In addition, we discuss the role of NK cell receptors in generation and maintenance of memory NK cells. Final part of this review illustrates how the NK cell response and its viral regulation can be exploited in designing recombinant viral vectors able to induce robust and protective CD8+ T cell response.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaSeminars in Immunopathology
Brojčani podacivol. 36, br. 6, str. 641-650
p-ISSN1863-2297
e-ISSN1863-2300
DOIhttps://doi.org/10.1007/s00281-014-0441-9
URN:NBNurn:nbn:hr:184:853548
Datum objave publikacije2014-08-21
Datum objave publikacije2014-11
ProjektŠifra: 322693
Naziv (hrvatski): Strengthening adaptive immunity via innate immunity: enhancing the CD8 T cell response by using the NKG2D ligand expressed in a herpesvirus vector
Kratica: STADVINN
Pravna nadležnost: eu
Financijer: EC
Linija financiranja: FP7
URL dokumentahttp://link.springer.com/10.1007/s00281-014-0441-9
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2018-10-31 09:39:07