prikaz prve stranice dokumenta Ventricular diastolic dimension over maximal myocardial thickness is robust landmark of systolic impairment in patients with hypertrophic cardiomyopathy
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Ventricular diastolic dimension over maximal myocardial thickness is robust landmark of systolic impairment in patients with hypertrophic cardiomyopathy
Medical Science Monitor, 24 (2018); 1880-1886. https://doi.org/10.12659/MSM.906111
Boban, Marko; Pesa, Vladimir; Antić Kauzlarić, Helena; Brusich, Sandro; Rotim, Ante; Madžar, Tomislav; Žulj, Marinko; Včev, Aleksandar

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Boban, M., Pesa, V., Antić Kauzlarić, H., Brusich, S., Rotim, A., Madžar, T. ... Včev, A. (2018). Ventricular diastolic dimension over maximal myocardial thickness is robust landmark of systolic impairment in patients with hypertrophic cardiomyopathy. Medical Science Monitor, 24., 1880-1886. doi: 10.12659/MSM.906111

Boban, Marko, et al. "Ventricular diastolic dimension over maximal myocardial thickness is robust landmark of systolic impairment in patients with hypertrophic cardiomyopathy." Medical Science Monitor, vol. 24, 2018, str. 1880-1886. https://doi.org/10.12659/MSM.906111

Boban, Marko, Vladimir Pesa, Helena Antić Kauzlarić, Sandro Brusich, Ante Rotim, Tomislav Madžar, Marinko Žulj i Aleksandar Včev. "Ventricular diastolic dimension over maximal myocardial thickness is robust landmark of systolic impairment in patients with hypertrophic cardiomyopathy." Medical Science Monitor 24 (2018): 1880-1886. https://doi.org/10.12659/MSM.906111

Boban, M., et al. (2018) 'Ventricular diastolic dimension over maximal myocardial thickness is robust landmark of systolic impairment in patients with hypertrophic cardiomyopathy', Medical Science Monitor, 24, str. 1880-1886. doi: 10.12659/MSM.906111

Boban M, Pesa V, Antić Kauzlarić H, Brusich S, Rotim A, Madžar T, i sur.. Ventricular diastolic dimension over maximal myocardial thickness is robust landmark of systolic impairment in patients with hypertrophic cardiomyopathy. Medical Science Monitor [Internet]. 03.2018. [pristupljeno 12.11.2024.];24:1880-1886. doi: 10.12659/MSM.906111

M. Boban, et al., "Ventricular diastolic dimension over maximal myocardial thickness is robust landmark of systolic impairment in patients with hypertrophic cardiomyopathy", Medical Science Monitor, vol. 24, str. 1880-1886, Ožujak 2018. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:881955. [Citirano: 12.11.2024.]

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Naslov (engleski)Ventricular diastolic dimension over maximal myocardial thickness is robust landmark of systolic impairment in patients with hypertrophic cardiomyopathy
AutorMarko Boban
AutorVladimir Pesa
AutorHelena Antić Kauzlarić
AutorSandro Brusich
AutorAnte Rotim
AutorTomislav Madžar
AutorMarinko Žulj
AutorAleksandar Včev
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za internu medicinu)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
BACKGROUND The effects of focal hypertrophy on geometry of the left ventricle and systolic function have not been studied in patients with hypertrophic cardiomyopathy (HCM), despite the fact that the former is the most prominent disease characteristic. The aim of our study was to analyze systolic function over ventricle geometry, generating a functional index made from left ventricle end diastolic dimension (LVEDD) divided by end diastolic thickness of the region with maximal extent of hypertrophy and interventricular septum. MATERIAL AND METHODS Our hospital database of cardiac magnetic resonance was screened for HCM. Geometric functional index (GFI) was calculated for LVEDD over maximal end diastolic thickness (MaxEDT) giving GFI-M, while LVEDD over interventricular septum was expressed as GFI-I. There were 55 consecutive patients with HCM. RESULTS There were 43 males (78.2%) and 12 females (21.8%). The mean age was 52.3±16.7 years (range: 15.5-76.4 years). A significant difference of GFI was found for preserved versus impaired systolic function of the left ventricle (preserved systolic function); GFI-M 2.28±0.60 versus 3.66±0.50 (p<0.001), and GFI-I 2.75±0.88 versus 3.81±0.87 (p<0.001), respectively. Diagnostic value was tested using receiver operating curve (ROC) analyzes, with GFI-M area under curve (AUC)=0.959 (95% CI: 0.868-0.994); (p<0.001) and GFI-I-AUC=0.847 (0.724-0.930); (p<0.001). GFI-M was superior to GFI-I for appraisal of left ventricle systolic dysfunction in HCM; ΔAUC=0.112 (0.018-0.207); (p=0.020). CONCLUSIONS GFI is a simple tool, with high sensitivity and specificity for detecting impairment of systolic function in patients with HCM. Further studies would be necessary to investigate its clinical and prognostic impacts, as well as reproducibility with prospective validation.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaMedical Science Monitor
Brojčani podacivol. 24, str. 1880-1886
e-ISSN1643-3750
DOIhttps://doi.org/10.12659/MSM.906111
URN:NBNurn:nbn:hr:184:881955
Datum objave publikacije2018-03
URL dokumentahttps://www.medscimonit.com/download/index/idArt/906111
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2018-04-18 14:36:22