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Epidermal Malignant Tumors: Pathogenesis, Influence of UV Light and Apoptosis
Collegium antropologicum, 31 - Supplement 1 (2007), 1; 83-85. urn:nbn:hr:184:784640
Prpić Massari, Larisa; Kaštelan, Marija; Gruber, Franjo

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Prpić Massari, L., Kaštelan, M. i Gruber, F. (2007). Epidermal Malignant Tumors: Pathogenesis, Influence of UV Light and Apoptosis. Collegium antropologicum, 31 - Supplement 1. (1), 83-85. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:184:784640

Prpić Massari, Larisa, et al. "Epidermal Malignant Tumors: Pathogenesis, Influence of UV Light and Apoptosis." Collegium antropologicum, vol. 31 - Supplement 1, br. 1, 2007, str. 83-85. https://urn.nsk.hr/urn:nbn:hr:184:784640

Prpić Massari, Larisa, Marija Kaštelan i Franjo Gruber. "Epidermal Malignant Tumors: Pathogenesis, Influence of UV Light and Apoptosis." Collegium antropologicum 31 - Supplement 1, br. 1 (2007): 83-85. https://urn.nsk.hr/urn:nbn:hr:184:784640

Prpić Massari, L., Kaštelan, M. i Gruber, F. (2007) 'Epidermal Malignant Tumors: Pathogenesis, Influence of UV Light and Apoptosis', Collegium antropologicum, 31 - Supplement 1(1), str. 83-85. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:184:784640 (Datum pristupa: 26.04.2024.)

Prpić Massari L, Kaštelan M, Gruber F. Epidermal Malignant Tumors: Pathogenesis, Influence of UV Light and Apoptosis. Collegium antropologicum [Internet]. 16.01.2007. [pristupljeno 26.04.2024.];31 - Supplement 1(1):83-85. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:784640

L. Prpić Massari, M. Kaštelan i F. Gruber, "Epidermal Malignant Tumors: Pathogenesis, Influence of UV Light and Apoptosis", Collegium antropologicum, vol. 31 - Supplement 1, br. 1, str. 83-85, Siječanj 2007. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:784640. [Citirano: 26.04.2024.]

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Podaci o radu
Naslov (engleski)Epidermal Malignant Tumors: Pathogenesis, Influence of UV Light and Apoptosis
AutorLarisa Prpić Massari
AutorMarija Kaštelan
AutorFranjo Gruber
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za dermatovenerologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Dermatovenerologija
Sažetak (engleski)
Basal cell carcinoma and squamous cell carcinoma, collectively termed non-melanoma skin cancers are the most commonmalignant tumors in humans. Basal cell carcinoma grows slowly and metastatic spread is very rare. Squamous cell carcinoma is characterized by infiltrative, destructive growth and metastasis. Long-term exposure of skin to UV light has a great impact on development of these epidermal malignancies. UV light induces cascade of events like well known DNA damage of keratinocytes as well as still completely undetermined influence on apoptotic process through expression of proapoptotic and antiapoptotic molecules. The major role in development of skin cancer is given to proapoptotic p53 molecule or tumor suppressor gene which mutation due to UV exposure leads to resistance of DNA-damaged cell to apoptosis. Other proapoptotic molecules such as Fas ligand (FasL) and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) are strongly expressed in basal cell carcinoma and squamous cell carcinoma that could be explained by the ability of tumor to escape the attack of immune system.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeStručni rad - Stručni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCollegium antropologicum
Brojčani podacivol. 31 - Supplement 1, br. 1, str. 83-85
p-ISSN0350-6134
URN:NBNurn:nbn:hr:184:784640
Datum objave publikacije2007-01-16
URL dokumentahttp://hrcak.srce.hr/27430
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2017-08-08 11:22:18