prikaz prve stranice dokumenta Does vitamin D supplementation impact serotonin levels? A systematic review and meta‐analysis
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Scientific paper - Review paper
Does vitamin D supplementation impact serotonin levels? A systematic review and meta‐analysis
Health Science Reports, 7 (2024), 8; e2276. https://doi.org/10.1002/hsr2.2276
Alimohammadi‐Kamalabadi, Malek; Ziaei, Somayeh; Hasani, Motahareh; Mohammadi, Shooka; Mehrbod, Milad; Morvaridi, Mehrnaz; Persad, Emma; Belančić, Andrej; Malekahmadi, Mahsa; Estêvão, Maria Dulce da Mota Antunes de Oliveira; Daneshzad, Elnaz; Heshmati, Javad

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Alimohammadi‐Kamalabadi, M., Ziaei, S., Hasani, M., Mohammadi, S., Mehrbod, M., Morvaridi, M. ... Heshmati, J. (2024). Does vitamin D supplementation impact serotonin levels? A systematic review and meta‐analysis. Health Science Reports, 7. (8). doi: 10.1002/hsr2.2276

Alimohammadi‐Kamalabadi, Malek, et al. "Does vitamin D supplementation impact serotonin levels? A systematic review and meta‐analysis." Health Science Reports, vol. 7, no. 8, 2024. https://doi.org/10.1002/hsr2.2276

Alimohammadi‐Kamalabadi, Malek, Somayeh Ziaei, Motahareh Hasani, Shooka Mohammadi, Milad Mehrbod, Mehrnaz Morvaridi, Emma Persad, et al. "Does vitamin D supplementation impact serotonin levels? A systematic review and meta‐analysis." Health Science Reports 7, no. 8 (2024). https://doi.org/10.1002/hsr2.2276

Alimohammadi‐Kamalabadi, M., et al. (2024) 'Does vitamin D supplementation impact serotonin levels? A systematic review and meta‐analysis', Health Science Reports, 7(8). doi: 10.1002/hsr2.2276

Alimohammadi‐Kamalabadi M, Ziaei S, Hasani M, Mohammadi S, Mehrbod M, Morvaridi M, and sur.. Does vitamin D supplementation impact serotonin levels? A systematic review and meta‐analysis. Health Science Reports [Internet]. 2024 July 30 [cited 2024 September 20];7(8). doi: 10.1002/hsr2.2276

M. Alimohammadi‐Kamalabadi, et al., "Does vitamin D supplementation impact serotonin levels? A systematic review and meta‐analysis", Health Science Reports, vol. 7, no. 8, July 2024. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:196756. [Accessed: 20 September 2024]

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Metadata
Title (english)Does vitamin D supplementation impact serotonin levels? A systematic review and meta‐analysis
AuthorMalek Alimohammadi‐Kamalabadi
AuthorSomayeh Ziaei
AuthorMotahareh Hasani
AuthorShooka Mohammadi
AuthorMilad Mehrbod
AuthorMehrnaz Morvaridi
AuthorEmma Persad
AuthorAndrej Belančić
AuthorMahsa Malekahmadi
AuthorMaria Dulce da Mota Antunes de Oliveira Estêvão
AuthorElnaz Daneshzad
AuthorJavad Heshmati
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Pharmacology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Pharmacology
Abstract (english)
Background and Aims: Vitamin D deficiency impacts a significant proportion of the world's population, and this deficiency has been linked to various conditions characterized by imbalanced serotonin regulation. The objective of this systematic review and meta-analysis was to evaluate the effect of vitamin D supplementation on serum serotonin levels. Methods: We conducted a comprehensive search of PubMed, Scopus, Cochrane Central for Randomized Clinical Trials, and Web of Science up to September 2022, without any language restrictions. The effect sizes were calculated using the standard mean difference (SMD) and 95% confidence interval (CI). Results: Six randomized clinical trials involving 356 participants were included in the analysis. Our findings indicated no significant changes in serotonin levels between the intervention and control groups (SMD: 0.24 ng/mL, 95% CI: −0.28, 0.75, p > 0.10). Subgroup analysis also did not reveal any significant changes in serotonin levels among children, participants with autism spectrum disorders, interventions lasting 10 weeks or longer, or those receiving vitamin D doses below 4000 IU/day. Conclusion: Although the results obtained in this systematic review are inconclusive, they support the need for further well-designed randomized trials to assess the potential role of vitamin D supplementation in regulating serotonin levels and potentially ameliorating depression and related disorders.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleHealth Science Reports
Numberingvol. 7, no. 8, e2276
p-ISSN2398-8835
e-ISSN2398-8835
DOIhttps://doi.org/10.1002/hsr2.2276
URN:NBNurn:nbn:hr:184:196756
Publication2024-07-30
Document URLhttps://onlinelibrary.wiley.com/doi/10.1002/hsr2.2276
Type of resourceText
Access conditionsRestricted access
Terms of useLicence In copyright icon
Created on2024-09-16 13:30:03