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master's thesis
Transkateterska implantacija aortalnog zaliska kod bolesnika niskog perioperativnog rizika
2024. urn:nbn:hr:184:867838
Pranić, Adrian
University of Rijeka
Faculty of Medicine
Department of Internal Medicine

Cite this document

Pranić, A. (2024). Transkateterska implantacija aortalnog zaliska kod bolesnika niskog perioperativnog rizika (Master's thesis). Rijeka: University of Rijeka, Faculty of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:867838

Pranić, Adrian. "Transkateterska implantacija aortalnog zaliska kod bolesnika niskog perioperativnog rizika." Master's thesis, University of Rijeka, Faculty of Medicine, 2024. https://urn.nsk.hr/urn:nbn:hr:184:867838

Pranić, Adrian. "Transkateterska implantacija aortalnog zaliska kod bolesnika niskog perioperativnog rizika." Master's thesis, University of Rijeka, Faculty of Medicine, 2024. https://urn.nsk.hr/urn:nbn:hr:184:867838

Pranić, A. (2024). 'Transkateterska implantacija aortalnog zaliska kod bolesnika niskog perioperativnog rizika', Master's thesis, University of Rijeka, Faculty of Medicine, accessed 16 November 2024, https://urn.nsk.hr/urn:nbn:hr:184:867838

Pranić A. Transkateterska implantacija aortalnog zaliska kod bolesnika niskog perioperativnog rizika [Master's thesis]. Rijeka: University of Rijeka, Faculty of Medicine; 2024 [cited 2024 November 16] Available at: https://urn.nsk.hr/urn:nbn:hr:184:867838

A. Pranić, "Transkateterska implantacija aortalnog zaliska kod bolesnika niskog perioperativnog rizika", Master's thesis, University of Rijeka, Faculty of Medicine, Rijeka, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:184:867838

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Metadata
TitleTranskateterska implantacija aortalnog zaliska kod bolesnika niskog perioperativnog rizika
Title (english)Transcatheter Aortic Valve Implantation in Low Perioperative Risk Patients
AuthorAdrian Pranić
MentorVjekoslav Tomulić (mentor)
Committee memberDavid Gobić (predsjednik povjerenstva)
Committee memberAlen Ružić (član povjerenstva)
Committee memberTomislav Jakljević (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Rijeka
Defense date and country2024-07-12, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract
Aortalna stenoza je suženje aortalne valvule uslijed promjena na listovima aortalnog zaliska, a koja posljedično dovodi do otežanog sistoličkog pražnjenja lijeve klijetke. Razlikujemo tri primarna uzroka aortalne stenoze, a to su kongenitalno abnormalna valvula, kalcificirana aortalna valvula i reumatska bolest aortalne valvule. Kada nastupe simptomi zaduhe, grudne boli i sinkope, prognoza je loša. Zamjena aortalnog zaliska je jedina dugoročna terapijska opcija, a izvodi se kirurškom operacijom ili transkateterskom implantacijom aortalnog zaliska (TAVI). Prema trenutačnim američkim i europskim smjernicama dozvoljava se upotreba TAVI kod bolesnika visokog perioperativnog rizika. Budući da je prevalencija aortalne stenoze u stalnom porastu, razmatra se mogućnost uvođenja transkateterske implantacije aortalnog zaliska kao opcije za liječenje bolesnika niskog perioperativnog rizika. U tijeku su randomizirane studije koje bi trebale postaviti temelje za nove smjernice.
Abstract (english)
Aortic stenosis is a narrowing of the aortic valve caused by changes in the leaflets of the aortic valve, which consequently leads to difficulty in systolic emptying of the left ventricle. We distinguish three primary causes of aortic stenosis, namely congenitally abnormal valve, calcified aortic valve and rheumatic aortic valve diseases. When symptoms of shortness of breath, chest pain and syncope occur, the prognosis is poor. Aortic valve replacement is the only long-term therapeutic option, and it is performed by surgery or transcatheter aortic valve implantation (TAVI). Current American and European guidelines allow the use of TAVI in patients with high perioperative risk. Since the prevalence of aortic stenosis is constantly increasing, the possibility of introducing transcatheter aortic valve implantation as an option for the treatment of patients with low perioperative risk is being considered. Randomized studies are underway that should lay the groundwork for new guidelines.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:867838
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2024-06-27 16:58:15