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master's thesis
Diagnosis and treatment of infective endocarditis - experience from the Clinic for infectious diseases at Clinical Hospital Centre Rijeka in a 10-year period
2024. urn:nbn:hr:184:385576
Gobac, Marin
University of Rijeka
Faculty of Medicine
Department of Infectious Diseases

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Gobac, M. (2024). Diagnosis and treatment of infective endocarditis - experience from the Clinic for infectious diseases at Clinical Hospital Centre Rijeka in a 10-year period (Master's thesis). Rijeka: University of Rijeka, Faculty of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:385576

Gobac, Marin. "Diagnosis and treatment of infective endocarditis - experience from the Clinic for infectious diseases at Clinical Hospital Centre Rijeka in a 10-year period." Master's thesis, University of Rijeka, Faculty of Medicine, 2024. https://urn.nsk.hr/urn:nbn:hr:184:385576

Gobac, Marin. "Diagnosis and treatment of infective endocarditis - experience from the Clinic for infectious diseases at Clinical Hospital Centre Rijeka in a 10-year period." Master's thesis, University of Rijeka, Faculty of Medicine, 2024. https://urn.nsk.hr/urn:nbn:hr:184:385576

Gobac, M. (2024). 'Diagnosis and treatment of infective endocarditis - experience from the Clinic for infectious diseases at Clinical Hospital Centre Rijeka in a 10-year period', Master's thesis, University of Rijeka, Faculty of Medicine, accessed 03 October 2024, https://urn.nsk.hr/urn:nbn:hr:184:385576

Gobac M. Diagnosis and treatment of infective endocarditis - experience from the Clinic for infectious diseases at Clinical Hospital Centre Rijeka in a 10-year period [Master's thesis]. Rijeka: University of Rijeka, Faculty of Medicine; 2024 [cited 2024 October 03] Available at: https://urn.nsk.hr/urn:nbn:hr:184:385576

M. Gobac, "Diagnosis and treatment of infective endocarditis - experience from the Clinic for infectious diseases at Clinical Hospital Centre Rijeka in a 10-year period", Master's thesis, University of Rijeka, Faculty of Medicine, Rijeka, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:184:385576

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Metadata
TitleDiagnosis and treatment of infective endocarditis - experience from the Clinic for infectious diseases at Clinical Hospital Centre Rijeka in a 10-year period
Title (croatian)Dijagnostika i liječenje infektivnog endokarditisa - iskustva iz Klinike za infektivne bolesti Kliničkog bolničkog centra Rijeka u 10-godišnjem periodu
AuthorMarin Gobac
MentorĐurđica Cekinović Grbeša (mentor)
Committee memberIrena Slavuljica (predsjednik povjerenstva)
Committee memberMarina Bubonja Šonje (član povjerenstva)
Committee memberTeodora Zaninović Jurjević (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Medicine
(Department of Infectious Diseases)
Rijeka
Defense date and country2024-07-12, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Infectology
Abstract
Infective endocarditis is a disease whose incidence is rising in patients of all ages; with male gender predominance of 2:1 ratio. Degenerative valvular diseases, an increase in the number of artificial valve procedures and a higher rate of nosocomial infections have led to the increase in the average age of patients with IE. IE is associated with high morbidity and mortality and, if left untreated, IE is considered to be always fatal. In recognizing this disease, the most important is to diagnose it on the basis of history and clinical examination. Modified Duke Criteria are generally accepted and applied in diagnostics today, even though they show low sensitivity without using imaging methods. Treatment of patients requires the joint involvement of infectious disease specialists, microbiologists and cardiologists, cardiac imaging experts and cardiac surgeons. Antimicrobial therapy is used in all cases due to the nature of infective agents; surgery is becoming the backbone in reducing mortality being used in up to 50% of patients. Adherence to therapeutic guidelines and indications for surgery can significantly improve the survival and quality of life of these patients.
Abstract (croatian)
Infektivni endokarditis bolest je čija je incidencija u porastu u bolesnika svih dobnih skupina; s dominacijom muškog spola u omjeru 2:1. Degenerativne valvularne bolesti, povećanje broja kirurških zahvata na zalistcima i veća stopa nozokomijalnih infekcija doveli su do porasta prosječne dobi bolesnika koji oboljevaju od infektivnog endokarditisa. Infektivni endokarditis povezan je s visokim morbiditetom i mortalitetom te, ako se pravovremeno ne liječi, smatra se uvijek fatalnim. U prepoznavanju ove bolesti najvažnije je dijagnosticirati je na temelju anamneze i kliničkog pregleda. Modificirani Dukeovi kriteriji danas su općenito prihvaćeni i primjenjuju se u dijagnostici, iako pokazuju nisku osjetljivost bez korištenja slikovnih metoda. Liječenje bolesnika zahtijeva zajednički angažman infektologa, mikrobiologa, kardiologa te kardiokirurga. Antimikrobna terapija koristi se u svim slučajevima zbog prirode uzročnika infekcije; kirurgija postaje okosnica u smanjenju smrtnosti i koristi se u do 50% pacijenata. Pridržavanje terapijskih smjernica i indikacija za operaciju može značajno poboljšati preživljenje i kvalitetu života ovih bolesnika.
Keywords
Keywords (croatian)
Languageenglish
URN:NBNurn:nbn:hr:184:385576
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2024-06-26 12:01:00