This thesis comprehensively explores the substantial impact of probiotics on skin health and their therapeutic potential across various dermatological conditions. It delves into the historical context of probiotics, tracing their use from ancient fermentation practices to contemporary biomedical research, highlighting their enduring relevance in promoting health and nutrition. The study systematically reviews the effects of different probiotic strains, such as Nitrobacter, Lactobacillus, and Bifidobacterium, on skin health, including their roles in enhancing immune responses, modulating microbial populations, and improving skin barrier functions. A critical analysis of the literature reveals probiotics' multifaceted benefits in treating skin conditions like acne, AD, psoriasis, SD, rosacea, and alopecia. These benefits range from antimicrobial and anti-inflammatory actions to the maintenance of skin barrier integrity and modulation of the skin's immune system. The thesis emphasizes the potential of probiotics to revolutionize skincare and dermatology by offering natural, effective treatment alternatives that leverage the skin-gut axis and the microbiome's health-promoting capabilities. Furthermore, the thesis underscores the need for further research to unravel the complex mechanisms through which probiotics influence skin health, identify optimal strains and formulations, and establish standardized therapeutic protocols. By highlighting the promising yet underexplored potential of probiotics in dermatology, critical appraisal of published research papers in this thesis lays the groundwork for future studies that could lead to innovative, microbiome-friendly skincare solutions and treatments for chronic skin disorders.