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Scientific paper - Review paper
Inhibitori protonske pumpe: kada, kome i koliko? – osvrt na racionalnu farmakoterapiju
Medicina Fluminensis : Medicina Fluminensis, 60 (2024), 1; 4-14. https://doi.org/10.21860/medflum2024_313680
Belančić, Andrej; Kresović, Andrea

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Belančić, A. & Kresović, A. (2024). Inhibitori protonske pumpe: kada, kome i koliko? – osvrt na racionalnu farmakoterapiju. Medicina Fluminensis : Medicina Fluminensis, 60. (1), 4-14. doi: 10.21860/medflum2024_313680

Belančić, Andrej and Andrea Kresović. "Inhibitori protonske pumpe: kada, kome i koliko? – osvrt na racionalnu farmakoterapiju." Medicina Fluminensis : Medicina Fluminensis, vol. 60, no. 1, 2024, pp. 4-14. https://doi.org/10.21860/medflum2024_313680

Belančić, Andrej and Andrea Kresović. "Inhibitori protonske pumpe: kada, kome i koliko? – osvrt na racionalnu farmakoterapiju." Medicina Fluminensis : Medicina Fluminensis 60, no. 1 (2024): 4-14. https://doi.org/10.21860/medflum2024_313680

Belančić, A. and Kresović, A. (2024) 'Inhibitori protonske pumpe: kada, kome i koliko? – osvrt na racionalnu farmakoterapiju', Medicina Fluminensis : Medicina Fluminensis, 60(1), pp. 4-14. doi: 10.21860/medflum2024_313680

Belančić A, Kresović A. Inhibitori protonske pumpe: kada, kome i koliko? – osvrt na racionalnu farmakoterapiju. Medicina Fluminensis : Medicina Fluminensis [Internet]. 2024 March 01 [cited 2024 May 05];60(1):4-14. doi: 10.21860/medflum2024_313680

A. Belančić and A. Kresović, "Inhibitori protonske pumpe: kada, kome i koliko? – osvrt na racionalnu farmakoterapiju", Medicina Fluminensis : Medicina Fluminensis, vol. 60, no. 1, pp. 4-14, March 2024. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:228717. [Accessed: 05 May 2024]

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Title (croatian)Inhibitori protonske pumpe: kada, kome i koliko? – osvrt na racionalnu farmakoterapiju
Title (english)Proton Pump Inhibitors: When, to Who and How Much? – Overview on Rational Pharmacotherapy
AuthorAndrej Belančić
AuthorAndrea Kresović
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Pharmacology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Clinical Pharmacology and Toxicology
Abstract (croatian)
Prevalencija neadekvatnog propisivanja inhibitora protonske pumpe (IPP) u rasponu je od 25 do 70 %, što zasigurno predstavlja značajan problem gledajući iz perspektive racionalne farmakoterapije/polipragmazije, farmakoekonomike, ali i farmakovigilancije. Kontinuirana edukacija, poznavanje aktualnih kliničkih smjernica, bolja i jasnija komunikacija (direktna i preko medicinske dokumentacije) između bolničkih specijalista, liječnika obiteljske medicine i samog bolesnika te redovita reevalvacija terapijske potrebe od neizmjerne su važnosti jer skupno rezultiraju propisivanjem lijeka u ispravnoj indikaciji, tijekom adekvatnog perioda i u potrebnoj dozi. Stoga je cilj ovog kratkog osvrta prikazati opravdane indikacije za propisivanje IPP-a, raspraviti o najčešćim zabludama i dilemama u kliničkoj praksi, evalvirati potencijalne rizike njihove neadekvatne i dugotrajne primjene, odnosno postaviti temelje za racionalniju farmakoterapiju.
Abstract (english)
The prevalence of inadequate prescribing of proton pump inhibitors (PPIs) is in the range of 25-70%, which is certainly a significant problem when viewed from the perspective of rational pharmacotherapy/polypragmasia, pharmacoeconomics, but also pharmacovigilance. Continuous education, knowledge of clinical guidelines, better and clearer communication (direct and through medical records) between hospital specialists, family physicians and the patient himself, as well as regular reevaluation of the therapeutic need are of immense importance because they collectively result in prescribing the drug in the correct indication, through an adequate period and in the required dose. Therefore, the aim of this short review is to present justified indications for prescribing PPIs, discuss the most common misconceptions and dilemmas in clinical practice, evaluate the potential risks of their inadequate and long-term use, and lay the foundation for rational pharmacotherapy principles.
Keywords (croatian)
Keywords (english)
Languagecroatian
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleMedicina Fluminensis : Medicina Fluminensis
Numberingvol. 60, no. 1, pp. 4-14
p-ISSN1847-6864
e-ISSN1848-820X
DOIhttps://doi.org/10.21860/medflum2024_313680
URN:NBNurn:nbn:hr:184:228717
Publication2024-03-01
Document URLhttps://hrcak.srce.hr/313680
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2024-03-01 09:06:22