Ebola is a hemorrhagic virus disease with high lethality for which no vaccine or adequate treatment has still been found. The Ebola epidemic which marked year 2014 started in December 2013, and is still actual, according to latest information. The epidemic spread to a number of African countries in which around 25000 people were infected, of which about 10000 died. Epicentres are found in countries of Guinea, Liberia and Sierra Leone, in which the disease lead to enormous consequences which are greater than just medical. High mobility sustained activity of the epidemic and contributed to reinfection of previously secure areas, so the disease spread to the neighbouring countries (Mali, Nigeria, Senegal) in which fast and adequate reaction of primarily local forces, with lesser help coming from outside, prevented a bigger epidemic spread. Besides the virus itself, reasons for such a great epidemic spread can be found in mistrust in the healthcare system, fear and panic, as well as big resistance from the community which even lead to death cases. Importance of informing and active involvement of local community is indisputable, as well as respect and understanding of their customs. Investment in healthcare system and education must not be put aside from the main goal – development of adequate treatment and vaccine for this disease.