Psychosomatic disorders in children and adolescents are physical illnesses paired with a lesion of the affected organ or organ system, and are caused by the interaction of somatic factors with psychological ones that enhance the development of the illness. The development of psychosomatic disorders today is most often interpreted using an integrative etiopathogenetic model, which emphasizes the interpersonal influence of many psychobiological factors, with alexithymia often present. Diagnostic obstacles can be the uncritical nature of the patients themselves, i.e. their parents, or the somatic symptoms can be so pronounced that the possibility of performing quality psychodiagnostics escapes. The most common diagnoses associated with psychosomatic problems include bronchial asthma, stomach and duodenal ulcers, inflammatory bowel diseases and atopic dermatitis, and they can be intertwined with each other, as well as with other illnesses. An integrative approach is also sought therapeutically, although due to the severity of the symptoms somatic treatment often has an advantage over psychotherapy, which, in addition to psychodynamic one, also uses cognitive-behavioral therapy. In psychosomatic patients, the role of the competent pediatrician and family or school medicine doctor is important in terms of recognizing the psychological aspects of the illness, and if necessary, they can also apply simple psychotherapeutic interventions to work through conflict and stress, along with relaxation skills.