Assessment of internal derangement of the temporomandibular joint according to the concentration of salivary cytokines in patients with spondyloarthritis

Laškarin, Ana-Marija; Laškarin, Gordana; Kehler, Tatjana; Gržić, Renata; Dulčić, Nikša

prikaz prve stranice dokumenta Assessment of internal derangement of the temporomandibular joint according to the concentration of salivary cytokines in patients with spondyloarthritis

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Scientific paper - Original scientific paper

Assessment of internal derangement of the temporomandibular joint according to the concentration of salivary cytokines in patients with spondyloarthritis

Medical hypotheses, 170 (2023), 23; 111000. urn:nbn:hr:184:369754

Laškarin, Ana-Marija; Laškarin, Gordana; Kehler, Tatjana; Gržić, Renata; Dulčić, Nikša

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APA 6th Edition

Laškarin, A. M., Laškarin, G., Kehler, T., Gržić, R. & Dulčić, N. (2023). Assessment of internal derangement of the temporomandibular joint according to the concentration of salivary cytokines in patients with spondyloarthritis. Medical hypotheses, 170. (23). Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:369754

MLA 8th Edition

Laškarin, Ana Marija, et al. "Assessment of internal derangement of the temporomandibular joint according to the concentration of salivary cytokines in patients with spondyloarthritis." Medical hypotheses, vol. 170, no. 23, 2023. https://urn.nsk.hr/urn:nbn:hr:184:369754

Chicago 17th Edition

Laškarin, Ana Marija, Gordana Laškarin, Tatjana Kehler, Renata Gržić and Nikša Dulčić. "Assessment of internal derangement of the temporomandibular joint according to the concentration of salivary cytokines in patients with spondyloarthritis." Medical hypotheses 170, no. 23 (2023). https://urn.nsk.hr/urn:nbn:hr:184:369754

Harvard

Laškarin, A. M., et al. (2023) 'Assessment of internal derangement of the temporomandibular joint according to the concentration of salivary cytokines in patients with spondyloarthritis', Medical hypotheses, 170(23). Available at: https://urn.nsk.hr/urn:nbn:hr:184:369754 (Accessed 14 November 2024)

Vancouver

Laškarin AM, Laškarin G, Kehler T, Gržić R, Dulčić N. Assessment of internal derangement of the temporomandibular joint according to the concentration of salivary cytokines in patients with spondyloarthritis. Medical hypotheses [Internet]. 2023 January 01 [cited 2024 November 14];170(23). Available at: https://urn.nsk.hr/urn:nbn:hr:184:369754

IEEE

A. M. Laškarin, G. Laškarin, T. Kehler, R. Gržić and N. Dulčić, "Assessment of internal derangement of the temporomandibular joint according to the concentration of salivary cytokines in patients with spondyloarthritis", Medical hypotheses, vol. 170, no. 23, January 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:369754. [Accessed: 14 November 2024]

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Title (english)	Assessment of internal derangement of the temporomandibular joint according to the concentration of salivary cytokines in patients with spondyloarthritis
Author	Ana-Marija Laškarin
Author	Gordana Laškarin
Author	Tatjana Kehler
Author	Renata Gržić
Author	Nikša Dulčić
Author's institution	University of Rijeka (Faculty of Dental Medicine)
Author's institution	University of Rijeka Faculty of Medicine (Department of Physiology, Immunology and Pathophxsiology)
Author's institution	University of Rijeka Faculty of Medicine (Department of Rehabilitatiom Medicine)
Scientific / art field, discipline and subdiscipline	BIOMEDICINE AND HEALTHCARE Basic Medical Sciences Human Physiology
Scientific / art field, discipline and subdiscipline	BIOMEDICINE AND HEALTHCARE Dental Medicine
Scientific / art field, discipline and subdiscipline	BIOMEDICINE AND HEALTHCARE Clinical Medical Sciences Internal Medicine
Abstract (english)	Spondyloarthritis (SpA) is a group of autoinflammatory/autoimmune diseases that affects the spine and peripheral joints. Involvement of the cervical spine correlates with occurrence of temporomandibular disorders (TMDs). Proinflammatory cytokines, interleukin (IL)-23, IL-17A, and tumour necrosis factor-alpha (TNF-α) are significantly involved in the immunopathogenesis of SpA, and inflammation is one of the causes of TMDs. We hypothesised that internal derangement (ID) of temporomandibular joints (TMJs), as the most frequent TMDs in patients with SpA, could be associated with salivary pro-inflammatory markers and clinical activity of axial SpA, measured with laboratory methods or rheumatological indexes. If a statistically significant difference in the concentration of salivary IL-23, IL-17A or TNF-α exists between patients with symptomatic or asymptomatic ID and patients without TMDs, the diagnostic accuracy of certain cytokine(s) for ID can be calculated. The diagnostic accuracy of the cytokine(s) could emphasise the inflammatory background of ID and possibly broaden therapeutic approaches for symptomatic ID in patients with SpA with biological drugs in addition to the routine application of occlusal splint and/or physical therapy.
Keywords (english)
Language	english
Publication type	Scientific paper - Original scientific paper
Publication status	Published
Peer review	Peer review - international
Publication version	Published version
Journal title	Medical hypotheses
Numbering	vol. 170, no. 23, 111000
p-ISSN	0306-9877
URN:NBN	urn:nbn:hr:184:369754
Publication	2023-01-01
Document URL	http://bib.irb.hr/1269959
Type of resource	Text
Access conditions	Institutional access
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Created on	2023-06-23 11:22:47