Surgical infections include infectious diseases that need to be treated with surgical procedures and infections that occur as a result of surgical interventions. Some of the infections which require surgical treatment are necrotizing infections of soft tissues such as necrotizing fasciitis, and gas and Fournier's gangrene, which are often accompanied by rapid clinical deterioration and require urgent surgical exploration and extensive debridement along with the use of antibiotics. Various localized and diffuse skin and subcutaneous infections also require surgical treatment. Abscess is a form of localized purulent infection that can be located under the skin, but also in body organs and cavities. In the case of a superficial abscess, it is necessary to make an incision and drain the purulent content, while in most deep abscesses the evacuation of the inflammatory content involves percutaneous needle aspiration. Tetanus is a life-threatening infectious disease whose prevention takes place every day in emergency surgical clinics in the form of hyperimmune tetanus immunoglobulins and tetanus vaccine. Regarding the risk of surgical site infection, surgical procedures can be divided into clean, clean-contaminated, contaminated, and septic surgical procedures. Surgical site infection can be superficial or deep, and it can affect organs and body cavities. Given that every operation poses a risk of infection, it is necessary to observe asepsis measures in surgery. In addition to intraoperative aseptic work, preventive measures for surgical site infection include preoperative procedures such as antibiotic prophylaxis and preoperative washing with antiseptics, as well as postoperative wound control and dressing procedures.