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Professional paper - Review paper
Stabilni izotopi 2H i 18O u dijagnostici I istraživanju pretilosti
Medicina Fluminensis : Medicina Fluminensis, 51 (2015), 2; 230-242. urn:nbn:hr:184:245828
Mance, Diana; Nadalin, Sergej; Lekić, Amalija; Ružić Baršić, Antonija

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Mance, D., Nadalin, S., Lekić, A. & Ružić Baršić, A. (2015). Stabilni izotopi 2H i 18O u dijagnostici I istraživanju pretilosti. Medicina Fluminensis : Medicina Fluminensis, 51. (2), 230-242. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:245828

Mance, Diana, et al. "Stabilni izotopi 2H i 18O u dijagnostici I istraživanju pretilosti." Medicina Fluminensis : Medicina Fluminensis, vol. 51, no. 2, 2015, pp. 230-242. https://urn.nsk.hr/urn:nbn:hr:184:245828

Mance, Diana, Sergej Nadalin, Amalija Lekić and Antonija Ružić Baršić. "Stabilni izotopi 2H i 18O u dijagnostici I istraživanju pretilosti." Medicina Fluminensis : Medicina Fluminensis 51, no. 2 (2015): 230-242. https://urn.nsk.hr/urn:nbn:hr:184:245828

Mance, D., et al. (2015) 'Stabilni izotopi 2H i 18O u dijagnostici I istraživanju pretilosti', Medicina Fluminensis : Medicina Fluminensis, 51(2), pp. 230-242. Available at: https://urn.nsk.hr/urn:nbn:hr:184:245828 (Accessed 05 December 2024)

Mance D, Nadalin S, Lekić A, Ružić Baršić A. Stabilni izotopi 2H i 18O u dijagnostici I istraživanju pretilosti. Medicina Fluminensis : Medicina Fluminensis [Internet]. 2015 June 01 [cited 2024 December 05];51(2):230-242. Available at: https://urn.nsk.hr/urn:nbn:hr:184:245828

D. Mance, S. Nadalin, A. Lekić and A. Ružić Baršić, "Stabilni izotopi 2H i 18O u dijagnostici I istraživanju pretilosti", Medicina Fluminensis : Medicina Fluminensis, vol. 51, no. 2, pp. 230-242, June 2015. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:245828. [Accessed: 05 December 2024]

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Metadata
Title (croatian)Stabilni izotopi 2H i 18O u dijagnostici I istraživanju pretilosti
Title (english)Stable isotopes 2H and 18O in the diagnosis and study of obesity
AuthorDiana Mance
AuthorSergej Nadalin
AuthorAmalija Lekić
AuthorAntonija Ružić Baršić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Radiology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Radiology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (croatian)
Pretilost je bolest u kojoj dolazi do prekomjernog nakupljanja masnog tkiva, što rezultira negativnim utjecajem na zdravlje pojedinca I skraćenim životnim vijekom. Jedan od najvažnijih problema u dijagnostici i istraživanju pretilosti je odabir najboljih metoda za njeno određivanje. Upotrebom vode obilježene stabilnim izotopima vodika i kisika (2H i 18O) moguće je precizno determinirati količinu masne mase u ukupnoj tjelesnoj masi i pouzdano odrediti ukupnu potrošnju energije organizma u višednevnom kontinuiranom periodu. U razjašnjavanju patofiziologije i etiopatogeneze pretilosti od posebnog je značaja i korištenje 2H i/ili 18O u praćenju metabolizma lipida, osobito masnih kiselina i triglicerida. Primjena metoda u kojima se koristi voda obilježena izotopima 2H i 18O ne zahtijeva hospitalizaciju ispitanika, pogodna je za terenska istraživanja na velikom broju ispitanika i primjenjiva je u svim dobnim skupinama. Unatoč mnogobrojnim prednostima, metode koje koriste vodu obilježenu 2H i 18O u istraživanju pretilosti u nas još uvijek nisu dovoljno poznate. Cilj ovog rada je pojasniti i približiti ih hrvatskoj liječničkoj struci, ali i ostalim zainteresiranim znanstvenicima i stručnjacima, kako bi se što uspješnije mogli pratiti svjetski trendovi pristupa problemu prekomjerne tjelesne mase i pretilosti. Osim toga, u radu su kritički razmotrene i druge metode koje se najčešće koriste u dijagnostici i istraživanju pretilosti.
Abstract (english)
Obesity is a disease characterized by excessive accumulation of body fat, resulting in negative impact on an individual’s health and shortened life span. One of the most important problems in the diagnosis and study of obesity is the selection of the best methods for its determination. Using water labeled with stable isotopes of hydrogen and oxygen (2H and 18O) it is possible to accurately determine the share of adipose tissue in body mass and reliably determine total energy expenditure of the organism in a continuous period of several days. The use of 2H and/or 18O is of special importance in clarifying the pathophysiology and etiopathogenesis of obesity as well as in monitoring the metabolism of lipids, particularly fatty acids and triglycerides. Application of the method in which water labeled with isotopes 2H and 18O is used does not require the hospitalization of participants, is suitable for field research on a large number of subjects, and is applicable to all age groups. Despite many advantages, the methods in which 2H and 18O labeled water is used for the study of obesity are still not common in Croatia. The aim of this paper is to familiarize the Croatian medical profession, as well as other interested scientists and experts with the methods, in order to successfully follow global trends in the approach to the problem of excessive body weight and obesity. In addition, the paper critically discusses some other methods that are commonly used in the diagnosis and study of obesity.
Keywords (croatian)
Keywords (english)
Languagecroatian
Publication typeProfessional paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleMedicina Fluminensis : Medicina Fluminensis
Numberingvol. 51, no. 2, pp. 230-242
p-ISSN0025-7729
URN:NBNurn:nbn:hr:184:245828
Publication2015-06-01
Document URLhttp://hrcak.srce.hr/139440
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-04-25 10:17:52