Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats

Župan, Gordana; Varljen, Jadranka; Eraković, Vesna; Mršić, Jasenka; Križ, Jasna; Simonić, Ante; Milin, Čedomila

prikaz prve stranice dokumenta Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats

Scientific paper - Original scientific paper

Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats

Croatica Chemica Acta, 68 (1995), 3; 485-490. urn:nbn:hr:184:107969

Župan, Gordana; Varljen, Jadranka; Eraković, Vesna; Mršić, Jasenka; Križ, Jasna; Simonić, Ante; Milin, Čedomila

Cite this document

APA 6th Edition

Župan, G., Varljen, J., Eraković, V., Mršić, J., Križ, J., Simonić, A. & Milin, Č. (1995). Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats. Croatica Chemica Acta, 68. (3), 485-490. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:107969

MLA 8th Edition

Župan, Gordana, et al. "Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats." Croatica Chemica Acta, vol. 68, no. 3, 1995, pp. 485-490. https://urn.nsk.hr/urn:nbn:hr:184:107969

Chicago 17th Edition

Župan, Gordana, Jadranka Varljen, Vesna Eraković, Jasenka Mršić, Jasna Križ, Ante Simonić and Čedomila Milin. "Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats." Croatica Chemica Acta 68, no. 3 (1995): 485-490. https://urn.nsk.hr/urn:nbn:hr:184:107969

Harvard

Župan, G., et al. (1995) 'Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats', Croatica Chemica Acta, 68(3), pp. 485-490. Available at: https://urn.nsk.hr/urn:nbn:hr:184:107969 (Accessed 14 February 2025)

Vancouver

Župan G, Varljen J, Eraković V, Mršić J, Križ J, Simonić A, and sur.. Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats. Croatica Chemica Acta [Internet]. 1995 [cited 2025 February 14];68(3):485-490. Available at: https://urn.nsk.hr/urn:nbn:hr:184:107969

IEEE

G. Župan, et al., "Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats", Croatica Chemica Acta, vol. 68, no. 3, pp. 485-490, 1995. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:107969. [Accessed: 14 February 2025]

Cite this item: https://urn.nsk.hr/urn:nbn:hr:184:107969

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Metadata

Title (english)	Accumulation Dynamics of the Brain Total Free Fatty Acids and Free Arachidonic Acid in the Models of Cerebral Hypoxia and Epilepsy in Rats
Author	Gordana Župan
Author	Jadranka Varljen
Author	Vesna Eraković
Author	Jasenka Mršić
Author	Jasna Križ
Author	Ante Simonić
Author	Čedomila Milin
Author's institution	University of Rijeka Faculty of Medicine (Department of Pharmacology)
Author's institution	University of Rijeka Faculty of Medicine (Department of Chemistry and Biochemistry)
Scientific / art field, discipline and subdiscipline	BIOMEDICINE AND HEALTHCARE Basic Medical Sciences Pharmacology
Scientific / art field, discipline and subdiscipline	BIOMEDICINE AND HEALTHCARE Basic Medical Sciences Medical Biochemistry
Abstract (english)	The aim of this study was to determine the dynamics of the brain free fatty acid (FFA) pool in rats exposed to: (a) controlled hypoxia, and (b) experimental epilepsy. Animals from group (a) were subjected to hypoxia procedure. Immediately, 5,15 or 60 minutes after losing the righting reflex, the animals were decapitated and brains were quickly removed. Animals from group (b) received penicillin (5000 U/5 pi) into the left lateral ventricle and were decapitated immediately, 5 or 15 minutes after the appearance of epileptic seizures. The FFA were quantified by gas chromatography. An increase in the total brain FFA content with the maximum level at 60 minutes after losing the righting reflex was detected in hypoxia- exposed rats. The highest level of the brain free arachidonic acid (FAA) was detected 15 minutes after hypoxia. Seizures also produced an increase in the total brain FFA and brain FAA, with a statistically significant level 5 minutes after the appearance of epileptic seizures.
Keywords (english)
Language	english
Publication type	Scientific paper - Original scientific paper
Publication status	Published
Peer review	Peer review
Publication version	Published version
Journal title	Croatica Chemica Acta
Numbering	vol. 68, no. 3, pp. 485-490
p-ISSN	0011-1643
e-ISSN	1334-417X
URN:NBN	urn:nbn:hr:184:107969
Publication	1995
Document URL	https://hrcak.srce.hr/136709
Type of resource	Text
Access conditions	Open access
Terms of use
Created on	2023-04-21 07:57:22