prikaz prve stranice dokumenta Kinetic Evaluation of Imidacloprid Degradation in Mice Organs Treated with Olive Oil Polyphenols Extract
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Scientific paper - Original scientific paper
Kinetic Evaluation of Imidacloprid Degradation in Mice Organs Treated with Olive Oil Polyphenols Extract
Croatica Chemica Acta, 81 (2008), 1; 203-209. urn:nbn:hr:184:646969
Broznić, Dalibor; Marinić, Jelena; Tota, Marin; Čanadi Jurešić, Gordana; Milin, Čedomila

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Broznić, D., Marinić, J., Tota, M., Čanadi Jurešić, G. & Milin, Č. (2008). Kinetic Evaluation of Imidacloprid Degradation in Mice Organs Treated with Olive Oil Polyphenols Extract. Croatica Chemica Acta, 81. (1), 203-209. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:646969

Broznić, Dalibor, et al. "Kinetic Evaluation of Imidacloprid Degradation in Mice Organs Treated with Olive Oil Polyphenols Extract." Croatica Chemica Acta, vol. 81, no. 1, 2008, pp. 203-209. https://urn.nsk.hr/urn:nbn:hr:184:646969

Broznić, Dalibor, Jelena Marinić, Marin Tota, Gordana Čanadi Jurešić and Čedomila Milin. "Kinetic Evaluation of Imidacloprid Degradation in Mice Organs Treated with Olive Oil Polyphenols Extract." Croatica Chemica Acta 81, no. 1 (2008): 203-209. https://urn.nsk.hr/urn:nbn:hr:184:646969

Broznić, D., et al. (2008) 'Kinetic Evaluation of Imidacloprid Degradation in Mice Organs Treated with Olive Oil Polyphenols Extract', Croatica Chemica Acta, 81(1), pp. 203-209. Available at: https://urn.nsk.hr/urn:nbn:hr:184:646969 (Accessed 15 November 2024)

Broznić D, Marinić J, Tota M, Čanadi Jurešić G, Milin Č. Kinetic Evaluation of Imidacloprid Degradation in Mice Organs Treated with Olive Oil Polyphenols Extract. Croatica Chemica Acta [Internet]. 2008 [cited 2024 November 15];81(1):203-209. Available at: https://urn.nsk.hr/urn:nbn:hr:184:646969

D. Broznić, J. Marinić, M. Tota, G. Čanadi Jurešić and Č. Milin, "Kinetic Evaluation of Imidacloprid Degradation in Mice Organs Treated with Olive Oil Polyphenols Extract", Croatica Chemica Acta, vol. 81, no. 1, pp. 203-209, 2008. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:646969. [Accessed: 15 November 2024]

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Metadata
Title (english)Kinetic Evaluation of Imidacloprid Degradation in Mice Organs Treated with Olive Oil Polyphenols Extract
AuthorDalibor Broznić
AuthorJelena Marinić
AuthorMarin Tota
AuthorGordana Čanadi Jurešić
AuthorČedomila Milin
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Chemistry and Biochemistry)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Medical Biochemistry
Abstract (english)
Imidacloprid is a highly effective insecticide, acting as agonists at the insect nicotinic acetylcholine receptor. Nevertheless, imidacloprid itself or its metabolites could exhibit toxicity in mammals. Imidacloprid biotransformation involves oxidative cleavage, releasing the 6-chloronicotinic acid. Therefore, the concentration of imidacloprid and 6-chloronicotinic acid was used to characterize degradation kinetics and distribution of imidacloprid in mice liver, kidneys and lungs. Additionally, the influence of olive oil polyphenols on imidacloprid metabolism was evaluated. Experimental animals were divided into three groups: control, IMI – imidacloprid treated mice (5 mg/kg) and (IMI + PP) – mice treated with polyphenols (10 mg/kg) for seven days before the administration of imidacloprid. Neither imidacloprid nor 6-chloronicotinic acid could be detected 48 hours after administration in IMI group, while complete degradation in the (IMI + PP) group was accomplished within 24 hours. Significantly higher rate constant and shorter half-life in (IMI + PP) group emphasize that polyphenols may diminish the toxicity of this pesticide.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCroatica Chemica Acta
Numberingvol. 81, no. 1, pp. 203-209
p-ISSN0011-1643
e-ISSN1334-417X
URN:NBNurn:nbn:hr:184:646969
Publication2008
Document URLhttps://hrcak.srce.hr/23448
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2023-04-21 07:01:50