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Scientific paper - Original scientific paper
A Histologic, Histomorphometric, and Immunohistochemical Evaluation of Anorganic Bovine Bone and Injectable Biphasic Calcium Phosphate in Humans: A Randomized Clinical Trial
International Journal of Molecular Sciences, 24 (2023), 6; 5539. https://doi.org/10.3390/ijms24065539
Tomas, Matej; Karl, Matej; Čandrlić, Marija; Matijević, Marko; Juzbašić, Martina; Peloza, Olga Cvijanović; Radetić, Ana Terezija Jerbić; Kuiš, Davor; Vidaković, Bruno; Ivanišević, Zrinka; Kačarević, Željka Perić

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Tomas, M., Karl, M., Čandrlić, M., Matijević, M., Juzbašić, M., Peloza, O. C. ... Kačarević, Ž. P. (2023). A Histologic, Histomorphometric, and Immunohistochemical Evaluation of Anorganic Bovine Bone and Injectable Biphasic Calcium Phosphate in Humans: A Randomized Clinical Trial. International Journal of Molecular Sciences, 24. (6). doi: 10.3390/ijms24065539

Tomas, Matej, et al. "A Histologic, Histomorphometric, and Immunohistochemical Evaluation of Anorganic Bovine Bone and Injectable Biphasic Calcium Phosphate in Humans: A Randomized Clinical Trial." International Journal of Molecular Sciences, vol. 24, no. 6, 2023. https://doi.org/10.3390/ijms24065539

Tomas, Matej, Matej Karl, Marija Čandrlić, Marko Matijević, Martina Juzbašić, Olga Cvijanović Peloza, Ana Terezija Jerbić Radetić, et al. "A Histologic, Histomorphometric, and Immunohistochemical Evaluation of Anorganic Bovine Bone and Injectable Biphasic Calcium Phosphate in Humans: A Randomized Clinical Trial." International Journal of Molecular Sciences 24, no. 6 (2023). https://doi.org/10.3390/ijms24065539

Tomas, M., et al. (2023) 'A Histologic, Histomorphometric, and Immunohistochemical Evaluation of Anorganic Bovine Bone and Injectable Biphasic Calcium Phosphate in Humans: A Randomized Clinical Trial', International Journal of Molecular Sciences, 24(6). doi: 10.3390/ijms24065539

Tomas M, Karl M, Čandrlić M, Matijević M, Juzbašić M, Peloza OC, and sur.. A Histologic, Histomorphometric, and Immunohistochemical Evaluation of Anorganic Bovine Bone and Injectable Biphasic Calcium Phosphate in Humans: A Randomized Clinical Trial. International Journal of Molecular Sciences [Internet]. 2023 March 14 [cited 2024 November 20];24(6). doi: 10.3390/ijms24065539

M. Tomas, et al., "A Histologic, Histomorphometric, and Immunohistochemical Evaluation of Anorganic Bovine Bone and Injectable Biphasic Calcium Phosphate in Humans: A Randomized Clinical Trial", International Journal of Molecular Sciences, vol. 24, no. 6, March 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:432871. [Accessed: 20 November 2024]

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Metadata
Title (english)A Histologic, Histomorphometric, and Immunohistochemical Evaluation of Anorganic Bovine Bone and Injectable Biphasic Calcium Phosphate in Humans: A Randomized Clinical Trial
AuthorMatej Tomas
AuthorMatej Karl
AuthorMarija Čandrlić
AuthorMarko Matijević
AuthorMartina Juzbašić
AuthorOlga Cvijanović Peloza
AuthorAna Terezija Jerbić Radetić
AuthorDavor Kuiš
AuthorBruno Vidaković
AuthorZrinka Ivanišević
AuthorŽeljka Perić Kačarević
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Anatomy)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Dental Medicine
Abstract (english)
Following trauma, chronic periapical process, or tooth extraction, a large loss of bone volume is noticed during the healing process. To facilitate the placement of dental implants, various surgical procedures are used for an optimal alveolar ridge profile, while maintaining adequate bone dimensions. The main aim of this study was to determine the healing ability (histologically and immunohistologically) of alveolar bone defects during augmentation with two different biomaterials: injectable biphasic calcium phosphate (BCP) and anorganic bovine bone (ABB). Thirty-eight subjects were randomly divided into two groups. The first group received the tested bone substitute biomaterial (BSB), i.e., BCP (maxresorb inject®), and the second group received an alternative to the gold standard, i.e., ABB (Bio-Oss®). The histopathological, histomorphometric, and immunohistochemical analyses gave comparable results for these bone substitute materials in terms of newly formed bone: (BCP: 39.91 ± 8.49%, ABB: 41.73 ± 13.99%), residual biomaterial (BCP: 28.61 ± 11.38%, ABB: 31.72 ± 15.52%), and soft tissue (BCP: 31.49 ± 11.09%, ABB: 26.54 ± 7.25%), with no significant difference found between the groups (p < 0.05, t-test), proving that BCP is equally suitable and successful for alveolar bone regeneration.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleInternational Journal of Molecular Sciences
Numberingvol. 24, no. 6, 5539
e-ISSN1422-0067
DOIhttps://doi.org/10.3390/ijms24065539
URN:NBNurn:nbn:hr:184:432871
Publication2023-03-14
ProjectNumber: IP-2020-02-7875
Title (croatian): Usporedba reparacijskog odgovora koštanog tkiva upotrebom dentina, ksenogenog biomaterijala i autologne kosti
Acronym: MgXBiomBone
Leader: Olga Peloza
Jurisdiction: Croatia
Funding stream: IP
Document URLhttps://www.mdpi.com/1422-0067/24/6/5539
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2023-04-19 08:35:56