prikaz prve stranice dokumenta Dynamics of CSBD Healing after Implementation of Dentin and Xenogeneic Bone Biomaterial
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Scientific paper - Original scientific paper
Dynamics of CSBD Healing after Implementation of Dentin and Xenogeneic Bone Biomaterial
Materials, 16 (2023), 4; 1600. https://doi.org/10.3390/ma16041600
Cvijanović Peloza, Olga; Jerbić Radetić, Ana Terezija; Baričić, Mirjana; Bukovac, Luka; Zoričić Cvek, Sanja

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Cvijanović Peloza, O., Jerbić Radetić, A. T., Baričić, M., Bukovac, L. & Zoričić Cvek, S. (2023). Dynamics of CSBD Healing after Implementation of Dentin and Xenogeneic Bone Biomaterial. Materials, 16. (4). doi: 10.3390/ma16041600

Cvijanović Peloza, Olga, et al. "Dynamics of CSBD Healing after Implementation of Dentin and Xenogeneic Bone Biomaterial." Materials, vol. 16, no. 4, 2023. https://doi.org/10.3390/ma16041600

Cvijanović Peloza, Olga, Ana Terezija Jerbić Radetić, Mirjana Baričić, Luka Bukovac and Sanja Zoričić Cvek. "Dynamics of CSBD Healing after Implementation of Dentin and Xenogeneic Bone Biomaterial." Materials 16, no. 4 (2023). https://doi.org/10.3390/ma16041600

Cvijanović Peloza, O., et al. (2023) 'Dynamics of CSBD Healing after Implementation of Dentin and Xenogeneic Bone Biomaterial', Materials, 16(4). doi: 10.3390/ma16041600

Cvijanović Peloza O, Jerbić Radetić AT, Baričić M, Bukovac L, Zoričić Cvek S. Dynamics of CSBD Healing after Implementation of Dentin and Xenogeneic Bone Biomaterial. Materials [Internet]. 2023 February 14 [cited 2025 April 02];16(4). doi: 10.3390/ma16041600

O. Cvijanović Peloza, A. T. Jerbić Radetić, M. Baričić, L. Bukovac and S. Zoričić Cvek, "Dynamics of CSBD Healing after Implementation of Dentin and Xenogeneic Bone Biomaterial", Materials, vol. 16, no. 4, February 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:885634. [Accessed: 02 April 2025]

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Metadata
Title (english)Dynamics of CSBD Healing after Implementation of Dentin and Xenogeneic Bone Biomaterial
AuthorOlga Cvijanović Peloza
AuthorAna Terezija Jerbić Radetić
AuthorMirjana Baričić
AuthorLuka Bukovac
AuthorSanja Zoričić Cvek
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Anatomy)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Anatomy
Abstract (english)
Autologous dentin is frequently used in guided bone regeneration due to its osteoinductive properties, which come from its similarity to native bone. On the other hand, the xenogeneic bone biomaterial Cerabone® serves as a biocompatible, but hardly resorbed biomaterial. During bone healing, an inflammatory, vascular, and osteogenic response occurs in which cytokines such as tumor necrosis factor-alpha (TNF-α), vascular endothelial growth factor (VEGF), and osteopontin (OPN) are released locally... More and systemically. The aim was to follow up the dynamics (on days 3, 7, 15, 21, and 30) of critical-sized bone defect (CSBD) healing after the implantation of bovine devitalized dentin, rat dentin, and xenogeneic bone biomaterial. For this purpose, histological and histomorphometric methods were employed. Additionally, serum concentrations of TNF-α, VEGF, and OPN were monitored in parallel to better understand the biomaterial-dependent systemic response in rats. At the last time interval, the results showed that the bone defect was bridged over in all three groups of biomaterials. The rat dentin group had the highest percentage of bone volume (BV/TV) and the least percentage of residual biomaterial (RB), which makes it the most optimal biomaterial for bone regeneration. Serum concentrations of the TNF-α, VEGF, and OPN refer to systemic response, which could be linked to intense bone remodeling between days 15 and 21 of the bone healing. Less
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleMaterials
Numberingvol. 16, no. 4, 1600
e-ISSN1996-1944
DOIhttps://doi.org/10.3390/ma16041600
URN:NBNurn:nbn:hr:184:885634
Publication2023-02-14
ProjectNumber: IP-2020-02-7875
Title (croatian): Usporedba reparacijskog odgovora koštanog tkiva upotrebom dentina, ksenogenog biomaterijala i autologne kosti
Acronym: MgXBiomBone
Leader: Olga Peloza
Jurisdiction: Croatia
Funding stream: IP
Document URLhttps://www.mdpi.com/1996-1944/16/4/1600
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2023-02-16 12:19:46
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