prikaz prve stranice dokumenta Predictive value of abdominal drain amylase for postoperative pancreatic fistula following gastric resection: A systematic review and meta- analysis
Access restricted to students and staff of home institution
Scientific paper - Review paper
Predictive value of abdominal drain amylase for postoperative pancreatic fistula following gastric resection: A systematic review and meta- analysis
European Journal of Surgical Oncology, 47 (2021), 6; 1244-1251. https://doi.org/10.1016/j.ejso.2020.12.005
Barcot, Ognjen; Boric, Matija; Cavar, Marija; Poropat, Goran; Puljak, Livia

Cite this document

Barcot, O., Boric, M., Cavar, M., Poropat, G. & Puljak, L. (2021). Predictive value of abdominal drain amylase for postoperative pancreatic fistula following gastric resection: A systematic review and meta- analysis. European Journal of Surgical Oncology, 47. (6), 1244-1251. doi: 10.1016/j.ejso.2020.12.005

Barcot, Ognjen, et al. "Predictive value of abdominal drain amylase for postoperative pancreatic fistula following gastric resection: A systematic review and meta- analysis." European Journal of Surgical Oncology, vol. 47, no. 6, 2021, pp. 1244-1251. https://doi.org/10.1016/j.ejso.2020.12.005

Barcot, Ognjen, Matija Boric, Marija Cavar, Goran Poropat and Livia Puljak. "Predictive value of abdominal drain amylase for postoperative pancreatic fistula following gastric resection: A systematic review and meta- analysis." European Journal of Surgical Oncology 47, no. 6 (2021): 1244-1251. https://doi.org/10.1016/j.ejso.2020.12.005

Barcot, O., et al. (2021) 'Predictive value of abdominal drain amylase for postoperative pancreatic fistula following gastric resection: A systematic review and meta- analysis', European Journal of Surgical Oncology, 47(6), pp. 1244-1251. doi: 10.1016/j.ejso.2020.12.005

Barcot O, Boric M, Cavar M, Poropat G, Puljak L. Predictive value of abdominal drain amylase for postoperative pancreatic fistula following gastric resection: A systematic review and meta- analysis. European Journal of Surgical Oncology [Internet]. 2021 [cited 2024 May 07];47(6):1244-1251. doi: 10.1016/j.ejso.2020.12.005

O. Barcot, M. Boric, M. Cavar, G. Poropat and L. Puljak, "Predictive value of abdominal drain amylase for postoperative pancreatic fistula following gastric resection: A systematic review and meta- analysis", European Journal of Surgical Oncology, vol. 47, no. 6, pp. 1244-1251, 2021. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:088751. [Accessed: 07 May 2024]

Please login to the repository to save this object to your list.
Metadata
Title (english)Predictive value of abdominal drain amylase for postoperative pancreatic fistula following gastric resection: A systematic review and meta- analysis
AuthorOgnjen Barcot
AuthorMatija Boric
AuthorMarija Cavar
MBZ: 276734
AuthorGoran Poropat
AuthorLivia Puljak
MBZ: 287953
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Background Radical dissection of lymph nodes, accompanying gastric cancer resection, can lead to collateral damage to the pancreas and development of postoperative pancreatic fistula (POPF). Methods We searched the Cochrane Library, MEDLINE, Embase, and Web of Science up to April 21, 2020, to identify studies documenting the value of abdominal drain amylase level (d-AMY) on postoperative day 1 (POD1) as a predictor of POPF after gastric surgery. The quality of selected studies was assessed using the QUADAS-2 tool. The diagnostic value of d-AMY on POD1 for prediction of POPF was first assessed by calculation of pooled estimates of sensitivity, specificity, likelihood ratios (LR), and the diagnostic odds ratio (DOR). Secondly, the accuracy was further demonstrated graphically with the hierarchical summary receiver operating curve (hSROC). PROSPERO registration number: CRD42020181145. Results DOR of nine studies (cases n = 1856) observing the occurrence of POPF after measurement of d-AMY on POD1 was 18.7 (95%CI: 10.0, 34.8), and the area under hSROC was 0.88 ± 0.02. The pooled sensitivity was 0.74 (95%CI: 0.66, 0.81) and specificity 0.84 (95%CI: 0.82, 0.86). The negative LR was at the lowest point of 0.16 (95%CI: 0.07, 0.37) at the cutoff value for d-AMY of 941 IU/L, while the positive LR ranged from 4.4 (cutoff 2119 IU/L) to 6.2 (cutoff 5000 IU/L). Conclusion d-AMY on POD1 can be used as an accurate and non- invasive predictor of POPF in the earliest stage of postoperative course following gastric cancer resection ; value ≤ 941 IU/L warrants early drain removal and low probability of POPF (any grade).
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleEuropean Journal of Surgical Oncology
Numberingvol. 47, no. 6, pp. 1244-1251
p-ISSN0748-7983
DOIhttps://doi.org/10.1016/j.ejso.2020.12.005
URN:NBNurn:nbn:hr:184:088751
Publication2021
Document URLhttp://bib.irb.hr/1125906
Type of resourceText
Access conditionsInstitutional access
Terms of useLicence In copyright icon
Created on2023-02-07 10:25:39