prikaz prve stranice dokumenta The Role of IL-6, 8, and 10, sTNFr, CRP, and Pancreatic Elastase in the Prediction of Systemic Complications in Patients with Acute Pancreatitis
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Scientific paper - Original scientific paper
The Role of IL-6, 8, and 10, sTNFr, CRP, and Pancreatic Elastase in the Prediction of Systemic Complications in Patients with Acute Pancreatitis
Gastroenterology Research and Practice, 2013 (2013); 1-6. https://doi.org/10.1155/2013/282645
Fišić, Elizabeta; Poropat, Goran; Bilić-Zulle, Lidija; Licul, Vanja; Milić, Sandra; Štimac, Davor

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Fišić, E., Poropat, G., Bilić Zulle, L., Licul, V., Milić, S. & Štimac, D. (2013). The Role of IL-6, 8, and 10, sTNFr, CRP, and Pancreatic Elastase in the Prediction of Systemic Complications in Patients with Acute Pancreatitis. Gastroenterology Research and Practice, 2013., 1-6. doi: 10.1155/2013/282645

Fišić, Elizabeta, et al. "The Role of IL-6, 8, and 10, sTNFr, CRP, and Pancreatic Elastase in the Prediction of Systemic Complications in Patients with Acute Pancreatitis." Gastroenterology Research and Practice, vol. 2013, 2013, pp. 1-6. https://doi.org/10.1155/2013/282645

Fišić, Elizabeta, Goran Poropat, Lidija Bilić Zulle, Vanja Licul, Sandra Milić and Davor Štimac. "The Role of IL-6, 8, and 10, sTNFr, CRP, and Pancreatic Elastase in the Prediction of Systemic Complications in Patients with Acute Pancreatitis." Gastroenterology Research and Practice 2013 (2013): 1-6. https://doi.org/10.1155/2013/282645

Fišić, E., et al. (2013) 'The Role of IL-6, 8, and 10, sTNFr, CRP, and Pancreatic Elastase in the Prediction of Systemic Complications in Patients with Acute Pancreatitis', Gastroenterology Research and Practice, 2013, pp. 1-6. doi: 10.1155/2013/282645

Fišić E, Poropat G, Bilić Zulle L, Licul V, Milić S, Štimac D. The Role of IL-6, 8, and 10, sTNFr, CRP, and Pancreatic Elastase in the Prediction of Systemic Complications in Patients with Acute Pancreatitis. Gastroenterology Research and Practice [Internet]. 2013 [cited 2024 November 17];2013:1-6. doi: 10.1155/2013/282645

E. Fišić, G. Poropat, L. Bilić Zulle, V. Licul, S. Milić and D. Štimac, "The Role of IL-6, 8, and 10, sTNFr, CRP, and Pancreatic Elastase in the Prediction of Systemic Complications in Patients with Acute Pancreatitis", Gastroenterology Research and Practice, vol. 2013, pp. 1-6, 2013. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:869562. [Accessed: 17 November 2024]

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Title (english)The Role of IL-6, 8, and 10, sTNFr, CRP, and Pancreatic Elastase in the Prediction of Systemic Complications in Patients with Acute Pancreatitis
AuthorElizabeta Fišić
AuthorGoran Poropat
AuthorLidija Bilić-Zulle
AuthorVanja Licul
AuthorSandra Milić
AuthorDavor Štimac
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Background and Aim. Early assessment of severity in acute pancreatitis (AP) is a key measure to provide rational and effective management. The aim of our study is to determine the prognostic value of interleukins (IL) 6, 8, and 10, soluble receptor for tumor necrosis factor (sTNFr), pancreatic elastase (E1), and C-reactive protein (CRP) as predictors of systemic complications in AP. Patients and Methods. A hundred and fifty patients with confirmed AP were enrolled in the study. The severity of AP was defined according to Atlanta criteria. Measurements of interleukins and sTNFr were performed on the first day of admission. CRP and E1 levels were assessed on admission and after 48 hours. ROC analysis was performed for all parameters. Results. Interleukins and sTNFr significantly differentiated patients with systemic complications from those without. Elevation of IL-6 showed the highest significance as a predictor (P = 0.001). CRP and elastase levels did not differ between mild and severe cases on admission, but reached statistical significance when measured on the third day (P = 0.002 and P = 0.001, resp.). Conclusion. Our study confirmed that IL-6, IL-8, IL-10, and sTNFr measured on admission, and CRP and pancreatic elastase measured on third day of admission represent valuable prognostic factors of severity and systemic complications of AP.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleGastroenterology Research and Practice
Numberingvol. 2013, pp. 1-6, 282645
p-ISSN1687-6121
e-ISSN1687-630X
DOIhttps://doi.org/10.1155/2013/282645
URN:NBNurn:nbn:hr:184:869562
Publication2013
Document URLhttp://www.hindawi.com/journals/grp/2013/282645/
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2022-09-19 13:48:09