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master's thesis
Etiopatogeneza, klinička slika i suvremena terapija gnojnog hidradenitisa
2022. urn:nbn:hr:184:715183
Marcelić, Lucija
University of Rijeka
Faculty of Medicine
Department of Dermatovenerology

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Marcelić, L. (2022). Etiopatogeneza, klinička slika i suvremena terapija gnojnog hidradenitisa (Master's thesis). Rijeka: University of Rijeka, Faculty of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:715183

Marcelić, Lucija. "Etiopatogeneza, klinička slika i suvremena terapija gnojnog hidradenitisa." Master's thesis, University of Rijeka, Faculty of Medicine, 2022. https://urn.nsk.hr/urn:nbn:hr:184:715183

Marcelić, Lucija. "Etiopatogeneza, klinička slika i suvremena terapija gnojnog hidradenitisa." Master's thesis, University of Rijeka, Faculty of Medicine, 2022. https://urn.nsk.hr/urn:nbn:hr:184:715183

Marcelić, L. (2022). 'Etiopatogeneza, klinička slika i suvremena terapija gnojnog hidradenitisa', Master's thesis, University of Rijeka, Faculty of Medicine, accessed 22 April 2024, https://urn.nsk.hr/urn:nbn:hr:184:715183

Marcelić L. Etiopatogeneza, klinička slika i suvremena terapija gnojnog hidradenitisa [Master's thesis]. Rijeka: University of Rijeka, Faculty of Medicine; 2022 [cited 2024 April 22] Available at: https://urn.nsk.hr/urn:nbn:hr:184:715183

L. Marcelić, "Etiopatogeneza, klinička slika i suvremena terapija gnojnog hidradenitisa", Master's thesis, University of Rijeka, Faculty of Medicine, Rijeka, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:184:715183

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Metadata
TitleEtiopatogeneza, klinička slika i suvremena terapija gnojnog hidradenitisa
Title (english)Etiopathogenesis, clinical manifestations and contemporary treatment of hidradenitis suppurativa
AuthorLucija Marcelić
MentorLarisa Prpić Massari (mentor)
Committee memberMarija Kaštelan (predsjednik povjerenstva)
Committee memberInes Brajac (član povjerenstva)
Committee memberMarko Zelić (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Medicine
(Department of Dermatovenerology)
Rijeka
Defense date and country2022-07-15, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Dermatovenerology
Abstract
Hidradenitis suppurativa je kronična upalna bolest kože koja primarno zahvaća aksile, perineum i submamarnu regiju. Bolest je također poznata pod nazivom acne inversa. Smatra se da je stopa prevalencije do 4%. Etiopatogeneza bolesti nije u potpunosti razjašnjena ali smatra se da je bolest posljedica folikularne okluzije, a ne upalnog ili infektivnog procesa u apokrinim žlijezdama. Klinički se bolest prezentira osjetljivim potkožnim čvorovima koji počinju u razdoblju oko puberteta. Čvorići mogu spontano rupturirati ili se spojiti tvoreći tako duboke bolne dermalne apscese. Posljedično može doći do nastanka fibroze i stvaranja opsežnih sinusnih puteva. Bolest se kasno dijagnosticira i oboljeli se suočavaju sa neuspješnim traženjem liječničke pomoći. Standardna terapija uključuje konzervativno i kirurško liječenje. Današnjim otkrićem novih terapija poput inhibitora čimbenika nekroze tumora alfa liječnici imaju sve više mogućnosti u borbi protiv ove teške bolesti.
Abstract (english)
Hydradenitis suppurativa is a chronic inflammatory skin disease that primarily affects the axilla, perineum and submammary region. The disease is also known as acne inversa. The prevalence rate is considered to be up to 4%. The etiopathogenesis of the disease is not fully elucidated but the disease is thought to be due to follicular occlusion rather than an inflammatory or infectious process in the apocrine glands. Clinically, the disease presents with sensitive subcutaneous nodules that begin around puberty. The nodules may spontaneously rupture or coalesce to form deep painful dermal abscesses. As a result, fibrosis can occur and extensive sinus pathways can form. The disease is diagnosed late and sufferers face unsuccessful seeking medical help. Standard therapy includes conservative and surgical treatment. With today’s discovery of new therapies like tumor necrosis factor alpha inhibitors doctors have more and more options to fight this serious disease.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:715183
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2022-07-10 14:01:50