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master's thesis
Usporedba perkutanih sustava za zatvaranje vaskularnog pristupa tijekom endovaskularnih zahvata
2022. urn:nbn:hr:184:709490
Košak, Luka
University of Rijeka
Faculty of Medicine
Department of Internal Medicine

Cite this document

Košak, L. (2022). Usporedba perkutanih sustava za zatvaranje vaskularnog pristupa tijekom endovaskularnih zahvata (Master's thesis). Rijeka: University of Rijeka, Faculty of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:709490

Košak, Luka. "Usporedba perkutanih sustava za zatvaranje vaskularnog pristupa tijekom endovaskularnih zahvata." Master's thesis, University of Rijeka, Faculty of Medicine, 2022. https://urn.nsk.hr/urn:nbn:hr:184:709490

Košak, Luka. "Usporedba perkutanih sustava za zatvaranje vaskularnog pristupa tijekom endovaskularnih zahvata." Master's thesis, University of Rijeka, Faculty of Medicine, 2022. https://urn.nsk.hr/urn:nbn:hr:184:709490

Košak, L. (2022). 'Usporedba perkutanih sustava za zatvaranje vaskularnog pristupa tijekom endovaskularnih zahvata', Master's thesis, University of Rijeka, Faculty of Medicine, accessed 03 January 2025, https://urn.nsk.hr/urn:nbn:hr:184:709490

Košak L. Usporedba perkutanih sustava za zatvaranje vaskularnog pristupa tijekom endovaskularnih zahvata [Master's thesis]. Rijeka: University of Rijeka, Faculty of Medicine; 2022 [cited 2025 January 03] Available at: https://urn.nsk.hr/urn:nbn:hr:184:709490

L. Košak, "Usporedba perkutanih sustava za zatvaranje vaskularnog pristupa tijekom endovaskularnih zahvata", Master's thesis, University of Rijeka, Faculty of Medicine, Rijeka, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:184:709490

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Metadata
TitleUsporedba perkutanih sustava za zatvaranje vaskularnog pristupa tijekom endovaskularnih zahvata
Title (english)Comparison of Percutaneous Closure Systems of Vascular Access Sites in Endovascular Procedures
AuthorLuka Košak
MentorVjekoslav Tomulić (mentor)
Committee memberTomislav Krčmar (predsjednik povjerenstva)
Committee memberSandro Brusich (član povjerenstva)
Committee memberZlatko Čubranić (član povjerenstva)
GranterUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Rijeka
Defense date and country2022-07-15, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract
Sustav za zatvaranje vaskularnog pristupa čini uređaj koji ima mogućnost postizanja trenutne hemostaze mjesta punkcije većih od 8Fr. Perclose ProGlide je perkutani sustav za zatvaranje endovaskularnog pristupa temeljen na šavovima, dok je MANTA VCD sustav za zatvaranje temeljen na kolagenu. Retrospektivnom kohortnom studijom uspoređena je učestalost pojave komplikacija prema BARC i VARC-3 kriterijima za krvarenje uz usporedbu ostalih čimbenika koji mogu utjecati na primarnu varijablu. Uspoređivana su dva najčešće korištena perkutana sustava za zatvaranje u Kliničkom bolničkom centru Rijeka u razdoblju od 2016. do 2021. godine. U istraživanje je uključeno ukupno 189 bolesnika, prosječne starosti 79 godina (63% udjela muškog spola). Femoralni vaskularni pristup zatvoren je dvostrukim Perclose ProGlide uređajem u 91 bolesnika, dok je 18Fr MANTA VCD korišten u 98 bolesnika. Rezultati pokazuju da ProGlide kohorta ima značajno češće komplikacije blažeg stupnja, dok MANTA VCD sustav uzrokuje neznačajno češće teže komplikacije koje imaju veći utjecaj na ukupnu kvalitetu života nakon zahvata. Kako blage komplikacije (VARC 1) najčešće ne zahtijevaju terapiju i ne utječu na prognozu bolesnika te se nerijetko samo prate, a analizom isključivo težih komplikacija ne pronalazimo značajne razlike, iako ProGlide kohorta ima neznačajno bolje rezultate, zaključujemo da niti jedan vaskularni sustav za zatvaranje nije značajno uspješniji. Stoga su nužna daljnja istraživanja o učestalosti VARC-3 komplikacija krvarenja iz drugih centara i s većim brojem sudionika, te naknadno sažimanje podataka u meta-analizu koja će, uzevši u obzir sve rezultate, dovesti do definitivnog zaključka.
Abstract (english)
The vascular access closure device is a medical device used for immediate hemostasis of puncture sites greater than 8Fr. Perclose ProGlide is a percutaneous suture-mediated endovascular access site closure system, while MANTA VCD is a collagen-based closure system. This retrospective cohort study compared complications according to BARC and VARC-3 criteria for bleeding and other variables that may affect the primary variable. The comparison was made between the two most frequently used percutaneous closure systems in Clinical Hospital Center Rijeka from 2016 to 2021. A total of 189 patients were included in the study, with an average age of 79 (63% male). Femoral vascular access site was closed with a double Perclose ProGlide device in 91 patients, while 18Fr MANTA VCD was used in 98 patients. The results show that the ProGlide cohort has significantly more common mild complications, while the MANTA VCD system causes insignificantly more severe complications that have a greater impact on overall quality of life. As mild complications (VARC 1) usually do not require therapy nor affect the prognosis and are often only monitored, while the results of severe complications are insignificant, although the ProGlide cohort has slightly better results, we conclude that no vascular closure system is significantly more successful. Therefore, further VARC-3 research on bleeding complications, from other centers and with a larger number of participants, is needed with subsequent summarization of data into a meta-analysis that will lead to a definitive conclusion.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:709490
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2022-07-08 10:16:11