prikaz prve stranice dokumenta Soluble adhesion molecules in patients with acute coronary syndrome after percutaneous coronary intervention with drug-coated balloon, drug-eluting stent or bare metal stent
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Scientific paper - Original scientific paper
Soluble adhesion molecules in patients with acute coronary syndrome after percutaneous coronary intervention with drug-coated balloon, drug-eluting stent or bare metal stent
Medical hypotheses, 95 (2016); 20-23. https://doi.org/10.1016/j.mehy.2016.08.008
Tomulić, Vjekoslav; Gobić, David; Lulić, Davorka; Židan, David; Zaputović, Luka

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Tomulić, V., Gobić, D., Lulić, D., Židan, D. & Zaputović, L. (2016). Soluble adhesion molecules in patients with acute coronary syndrome after percutaneous coronary intervention with drug-coated balloon, drug-eluting stent or bare metal stent. Medical hypotheses, 95., 20-23. doi: 10.1016/j.mehy.2016.08.008

Tomulić, Vjekoslav, et al. "Soluble adhesion molecules in patients with acute coronary syndrome after percutaneous coronary intervention with drug-coated balloon, drug-eluting stent or bare metal stent." Medical hypotheses, vol. 95, 2016, pp. 20-23. https://doi.org/10.1016/j.mehy.2016.08.008

Tomulić, Vjekoslav, David Gobić, Davorka Lulić, David Židan and Luka Zaputović. "Soluble adhesion molecules in patients with acute coronary syndrome after percutaneous coronary intervention with drug-coated balloon, drug-eluting stent or bare metal stent." Medical hypotheses 95 (2016): 20-23. https://doi.org/10.1016/j.mehy.2016.08.008

Tomulić, V., et al. (2016) 'Soluble adhesion molecules in patients with acute coronary syndrome after percutaneous coronary intervention with drug-coated balloon, drug-eluting stent or bare metal stent', Medical hypotheses, 95, pp. 20-23. doi: 10.1016/j.mehy.2016.08.008

Tomulić V, Gobić D, Lulić D, Židan D, Zaputović L. Soluble adhesion molecules in patients with acute coronary syndrome after percutaneous coronary intervention with drug-coated balloon, drug-eluting stent or bare metal stent. Medical hypotheses [Internet]. 2016 [cited 2024 May 04];95:20-23. doi: 10.1016/j.mehy.2016.08.008

V. Tomulić, D. Gobić, D. Lulić, D. Židan and L. Zaputović, "Soluble adhesion molecules in patients with acute coronary syndrome after percutaneous coronary intervention with drug-coated balloon, drug-eluting stent or bare metal stent", Medical hypotheses, vol. 95, pp. 20-23, 2016. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:564182. [Accessed: 04 May 2024]

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Metadata
Title (english)Soluble adhesion molecules in patients with acute coronary syndrome after percutaneous coronary intervention with drug-coated balloon, drug-eluting stent or bare metal stent
AuthorVjekoslav Tomulić
AuthorDavid Gobić
AuthorDavorka Lulić
AuthorDavid Židan
AuthorLuka Zaputović
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Adhesion molecules play an important role in inflammation, atherosclerosis and coronary artery disease (CAD). These molecules are expressed on the surface of dysfunctional endothelial cells, causing inflammatory cells from the circulation to adhere and migrate through the endothelium. Their expression is upregulated in acute coronary syndrome (ACS) and after percutaneous coronary intervention (PCI). The contact between stent struts and endothelium upregulates endothelial cell gene expression, endothelial cell activation and inflammation. The paclitaxel or sirolimus eluting stents inhibited expression of adhesion molecules in several studies and reduced the incidence of major adverse cardiac events (MACE) after drug-eluting stent (DES) over bare metal stent (BMS) implantation. Therefore, we propose that elevated serum levels of the soluble adhesion molecules after primary PCI in patients treated with BMS or DES implantation versus drug-coated balloon (DCB) application to the vulnerable coronary plaque might be a predictor of MACE and further adverse outcomes. Consequently, DCB-only strategy in patients with ACS might be a superior approach in comparison to BMS implantation and non-inferior approach when compared to DES implantation.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleMedical hypotheses
Numberingvol. 95, pp. 20-23
p-ISSN0306-9877
DOIhttps://doi.org/10.1016/j.mehy.2016.08.008
URN:NBNurn:nbn:hr:184:564182
Publication2016
Document URLhttp://bib.irb.hr/888445
Type of resourceText
Access conditionsInstitutional access
Terms of useLicence In copyright icon
Created on2022-03-09 12:55:00