Rapid fatal acute peripheral T-cell lymphoma 
associated with IgG plasma cell leukemia and IgA 
hypergammaglobulinemia : case report

Jonjić, Nives; Seili-Bekafigo, Irena; Fučkar Čupić, Dora; Lučin, Ksenija; Duletić- Načinović, Antica; Valković, Toni

doi:10.1097/PAI.0000000000000361

prikaz prve stranice dokumenta Rapid fatal acute peripheral T-cell lymphoma associated with IgG plasma cell leukemia and IgA hypergammaglobulinemia : case report

Scientific paper - Case study

Rapid fatal acute peripheral T-cell lymphoma associated with IgG plasma cell leukemia and IgA hypergammaglobulinemia : case report

Applied immunohistochemistry & molecular morphology, 24 (2016), 10; e89-e93. https://doi.org/10.1097/PAI.0000000000000361

Jonjić, Nives; Seili-Bekafigo, Irena; Fučkar Čupić, Dora; Lučin, Ksenija; Duletić- Načinović, Antica; Valković, Toni

Cite this document

APA 6th Edition

Jonjić, N., Seili Bekafigo, I., Fučkar Čupić, D., Lučin, K., Duletić Načinović, A. & Valković, T. (2016). Rapid fatal acute peripheral T-cell lymphoma associated with IgG plasma cell leukemia and IgA hypergammaglobulinemia : case report. Applied immunohistochemistry & molecular morphology, 24. (10), e89-e93. doi: 10.1097/PAI.0000000000000361

MLA 8th Edition

Jonjić, Nives, et al. "Rapid fatal acute peripheral T-cell lymphoma associated with IgG plasma cell leukemia and IgA hypergammaglobulinemia : case report." Applied immunohistochemistry & molecular morphology, vol. 24, no. 10, 2016, pp. e89-e93. https://doi.org/10.1097/PAI.0000000000000361

Chicago 17th Edition

Jonjić, Nives, Irena Seili Bekafigo, Dora Fučkar Čupić, Ksenija Lučin, Antica Duletić Načinović and Toni Valković. "Rapid fatal acute peripheral T-cell lymphoma associated with IgG plasma cell leukemia and IgA hypergammaglobulinemia : case report." Applied immunohistochemistry & molecular morphology 24, no. 10 (2016): e89-e93. https://doi.org/10.1097/PAI.0000000000000361

Harvard

Jonjić, N., et al. (2016) 'Rapid fatal acute peripheral T-cell lymphoma associated with IgG plasma cell leukemia and IgA hypergammaglobulinemia : case report', Applied immunohistochemistry & molecular morphology, 24(10), pp. e89-e93. doi: 10.1097/PAI.0000000000000361

Vancouver

Jonjić N, Seili Bekafigo I, Fučkar Čupić D, Lučin K, Duletić Načinović A, Valković T. Rapid fatal acute peripheral T-cell lymphoma associated with IgG plasma cell leukemia and IgA hypergammaglobulinemia : case report. Applied immunohistochemistry & molecular morphology [Internet]. 2016 [cited 2024 December 02];24(10):e89-e93. doi: 10.1097/PAI.0000000000000361

IEEE

N. Jonjić, I. Seili Bekafigo, D. Fučkar Čupić, K. Lučin, A. Duletić Načinović and T. Valković, "Rapid fatal acute peripheral T-cell lymphoma associated with IgG plasma cell leukemia and IgA hypergammaglobulinemia : case report", Applied immunohistochemistry & molecular morphology, vol. 24, no. 10, pp. e89-e93, 2016. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:846403. [Accessed: 02 December 2024]

Cite this item: https://urn.nsk.hr/urn:nbn:hr:184:846403

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Metadata

Title (english)	Rapid fatal acute peripheral T-cell lymphoma associated with IgG plasma cell leukemia and IgA hypergammaglobulinemia : case report
Author	Nives Jonjić
Author	Irena Seili-Bekafigo
Author	Dora Fučkar Čupić
Author	Ksenija Lučin
Author	Antica Duletić- Načinović
Author	Toni Valković
Author's institution	University of Rijeka Faculty of Medicine (Department of Internal Medicine)
Author's institution	University of Rijeka Faculty of Medicine (Department of General Pathology and Pathological Anatomy)
Scientific / art field, discipline and subdiscipline	BIOMEDICINE AND HEALTHCARE Clinical Medical Sciences Pathology
Scientific / art field, discipline and subdiscipline	BIOMEDICINE AND HEALTHCARE Clinical Medical Sciences Internal Medicine
Abstract (english)	Simultaneous occurrence of T-cell and B-cell neoplasms is rare and etiologic relationships between these two malignancies are poorly understood. We describe a case of 66-year-old woman who was admitted to the hospital because of fever, hemoptysis, lymphadenopathy, and skin rash. Enlarged lymph nodes in the axillary, pectoral, paratracheal and periportal regions, as well as slight hepato- and splenomegaly were confirmed. Peripheral blood smear revealed rouleaux formation and numerous circulating plasma cells, with plasmacytoid lymphocytes. Immunofixation- electrophoresis detected a monoclonal band defined as IgG-lambda light chains with broad band polyclonal IgA. The patient died from abrupt splenic rupture before diagnostic work-up was finished. Postmortem examination revealed infiltration of atypical lymphoid cells exhibiting high proliferative activity admixed with typical and atypical plasma cells in several organs. Thus plasma cell leukemia (IgG-lambda) as a rare and aggressive variant of plasma cell myeloma in present case was associated with aggressive peripheral T cell lymphoma and polyclonal (IgA) plasmacytosis.
Keywords (english)
Language	english
Publication type	Scientific paper - Case study
Publication status	Published
Peer review	Peer review - international
Publication version	Submitted version
Journal title	Applied immunohistochemistry & molecular morphology
Numbering	vol. 24, no. 10, pp. e89-e93
p-ISSN	1541-2016
DOI	https://doi.org/10.1097/PAI.0000000000000361
URN:NBN	urn:nbn:hr:184:846403
Publication	2016
Document URL	http://bib.irb.hr/813361
Type of resource	Text
Access conditions	Open access
Terms of use
Created on	2022-03-04 12:09:05