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Scientific paper - Original scientific paper
Mass spectrometry-based glycomic profiling of the total IgG and total proteome N-glycomes isolated from follicular fluid
Biomolecular Concepts, 11 (2020), 1; 153-171. https://doi.org/10.1515/bmc-2020-0015
Klobučar, Marko; Dević Pavlić, Sanja; Car, Iris; Smiljan Severinski, Neda; Tramišak Milaković, Tamara; Radojčić Badovinac, Anđelka; Kraljević Pavelić, Sandra

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Klobučar, M., Dević Pavlić, S., Car, I., Smiljan Severinski, N., Tramišak Milaković, T., Radojčić Badovinac, A. & Kraljević Pavelić, S. (2020). Mass spectrometry-based glycomic profiling of the total IgG and total proteome N-glycomes isolated from follicular fluid. Biomolecular Concepts, 11. (1), 153-171. doi: 10.1515/bmc-2020-0015

Klobučar, Marko, et al. "Mass spectrometry-based glycomic profiling of the total IgG and total proteome N-glycomes isolated from follicular fluid." Biomolecular Concepts, vol. 11, no. 1, 2020, pp. 153-171. https://doi.org/10.1515/bmc-2020-0015

Klobučar, Marko, Sanja Dević Pavlić, Iris Car, Neda Smiljan Severinski, Tamara Tramišak Milaković, Anđelka Radojčić Badovinac and Sandra Kraljević Pavelić. "Mass spectrometry-based glycomic profiling of the total IgG and total proteome N-glycomes isolated from follicular fluid." Biomolecular Concepts 11, no. 1 (2020): 153-171. https://doi.org/10.1515/bmc-2020-0015

Klobučar, M., et al. (2020) 'Mass spectrometry-based glycomic profiling of the total IgG and total proteome N-glycomes isolated from follicular fluid', Biomolecular Concepts, 11(1), pp. 153-171. doi: 10.1515/bmc-2020-0015

Klobučar M, Dević Pavlić S, Car I, Smiljan Severinski N, Tramišak Milaković T, Radojčić Badovinac A, and sur.. Mass spectrometry-based glycomic profiling of the total IgG and total proteome N-glycomes isolated from follicular fluid. Biomolecular Concepts [Internet]. 2020 [cited 2024 December 09];11(1):153-171. doi: 10.1515/bmc-2020-0015

M. Klobučar, et al., "Mass spectrometry-based glycomic profiling of the total IgG and total proteome N-glycomes isolated from follicular fluid", Biomolecular Concepts, vol. 11, no. 1, pp. 153-171, 2020. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:581291. [Accessed: 09 December 2024]

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Metadata
Title (english)Mass spectrometry-based glycomic profiling of the total IgG and total proteome N-glycomes isolated from follicular fluid
AuthorMarko Klobučar
AuthorSanja Dević Pavlić
AuthorIris Car
AuthorNeda Smiljan Severinski
AuthorTamara Tramišak Milaković
AuthorAnđelka Radojčić Badovinac
AuthorSandra Kraljević Pavelić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Gynaecology and Obstetrics)
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Biotechnology
Abstract (english)
Couples with infertility issues have been assisted by in vitro fertilization reproduction technologies with high success rates of 50-80%. However, complications associated with ovarian stimulation remain, such as ovarian hyperstimulation. Oocyte quality is a significant factor impacting the outcome of in vitro fertilization procedures, but other processes are also critical for fertilization success. Increasing evidence points to aberrant inflammation as one of these critical processes reflected in molecular changes, including glycosylation of proteins. Here we report results from a MALDI-TOF-MS-based glycomic profiling of the total IgG and total proteome N-glycomes isolated from the follicular fluid obtained from patients undergoing fertilization through either (1) assisted reproduction by modified natural cycle or (2) controlled ovarian stimulation (GnRH antagonist, GnRH Ant) protocols. Significant inflammatory-related differences between analyzed N-glycomes were observed from samples and correlated with the ovarian stimulation protocol used in patients.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleBiomolecular Concepts
Numberingvol. 11, no. 1, pp. 153-171
p-ISSN1868-503X
DOIhttps://doi.org/10.1515/bmc-2020-0015
URN:NBNurn:nbn:hr:184:581291
Publication2020
Document URLhttp://bib.irb.hr/1103724
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) icon
Created on2022-02-24 13:57:39